Calcification, Physiologic
Research News and Information

Monday, November 23, 2009

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

29 Nov 2009 Osteosarcomas are the most prevalent primary bone tumors found in pediatric patients. To understand their molecular etiology, cell culture models are used to define disease mechanisms under controlled conditions. Many osteosarcoma cell lines (e.g., ... Read more...

Osteoblast differentiation is functionally associated with decreased AMP kinase activity.

29 Nov 2009 Osteoblasts, originating from mesenchymal stem cells, play a pivotal role in bone formation and mineralization. Several transcription factors including runt-related transcription factor 2 (Runx2) have been reported to be essential for osteoblast ... Read more...

Mineralized tissue formation by BMP2-transfected pulp stem cells.

30 Oct 2009 Previously, in vitro differentiation of odontoblasts was shown for dental pulp stem cells (DPSCs) transfected with bone morphogenetic protein-2 (Bmp2). For this study, we hypothesized that such cells also show potential for mineralized tissue ... Read more...

Latest indexed articles for 'Calcification, Physiologic'

These are the very latest articles for this heading:

• Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1). 29 Nov 2009
• Osteoblast differentiation is functionally associated with decreased AMP kinase activity. 29 Nov 2009
• Mineralized tissue formation by BMP2-transfected pulp stem cells. 30 Oct 2009
• Sustained epidermal growth factor receptor levels and activation by tethered ligand binding enhances osteogenic differentiation of multi-potent marrow stromal cells. 30 Oct 2009
• Stimulation of human mesenchymal stem cells and osteoblasts activities in vitro on silicon-releasable scaffolds. 29 Sep 2009
• Inhibition of glycogen synthase kinase-3beta attenuates glucocorticoid-induced bone loss. 23 Sep 2009
• In vivo performance of simvastatin-loaded electrospun spiral-wound polycaprolactone scaffolds in reconstruction of cranial bone defects in the rat model. 13 Sep 2009
• Asporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization. 12 Sep 2009
• Vascular calcification and bone disease: the calcification paradox. Sep 2009
• Human acid-labile subunit deficiency: clinical, endocrine and metabolic consequences. 30 Aug 2009
• Novel effect of biphasic electric current on in vitro osteogenesis and cytokine production in human mesenchymal stromal cells. 30 Aug 2009
• Variability in bone mineralization among purebred lines of meat-type chickens. 30 Aug 2009
• Enzyme complex containing carbohydrases and phytase improves growth performance and bone mineralization of broilers fed reduced nutrient corn-soybean-based diets. 30 Aug 2009
• Interference with cellular differentiation by D-serine through antagonism at N-methyl-D-aspartate receptors composed of NR1 and NR3A subunits in chondrocytes. 30 Aug 2009
• Distinctive anabolic roles of 1,25-dihydroxyvitamin D(3) and parathyroid hormone in teeth and mandible versus long bones. 25 Aug 2009
• Functional grading of mineral and collagen in the attachment of tendon to bone. 17 Aug 2009
• Dose-dependent effects of triiodothyronine on the osteogenic differentiation of rat bone marrow mesenchymal stem cells. 16 Aug 2009
• Biochemistry. The molecular basis of nacre formation. 11 Aug 2009
• An acidic matrix protein, Pif, is a key macromolecule for nacre formation. 11 Aug 2009
• Oxytocin deficiency impairs maternal skeletal remodeling. Aug 2009

See a longer list of these articles.

Technical information about 'Calcification, Physiologic'

Definition: Process by which organic tissue becomes hardened by the physiologic deposit of calcium salts.

Descriptor UI: D002113

Alternative terms: Calcification, Physiologic; Calcification, Physiological; Physiological Calcification; Physiologic Calcification; Bone Mineralization; Mineralization, Bone;

Related Mesh Headings: Bone Development; Osteogenesis;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G07.700.320.186; G07.700.320.500.325.377.625.100.175; G11.427.590.560.100.175;

History Note: 65; was CALCIFICATION 1963-64

Technical Notes: TOOTH CALCIFICATION is also available; DF: CALCIFICATION PHYSIOL