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Calcium Signaling - Physiology
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Definition of 'Calcium Signaling'

Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.

Common names: Calcium Signaling; Calcium Signalings; Signaling, Calcium; Signalings, Calcium; Calcium Spikes; Calcium Spike; Spike, Calcium; Spikes, Calcium; Calcium Waves; Calcium Wave; Wave, Calcium; Waves, Calcium; Calcium Oscillations; Calcium Oscillation; Oscillation, Calcium; Oscillations, Calcium

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Sunday, November 22, 2009

Odontoblast TRP channels and thermo/mechanical transmission.

30 Oct 2009 Odontoblasts function as mechanosensory receptors because of the expression of mechanosensitive channels in these cells. However, it is unclear if odontoblasts direct the signal transmission evoked by heat/cold or osmotic changes. This study ... Read more...


Ca2+ current versus Ca2+ channel cooperativity of exocytosis.

28 Sep 2009 Recently there has been significant interest and progress in the study of spatiotemporal dynamics of Ca(2+) that triggers exocytosis at a fast chemical synapse, which requires understanding the contribution of individual calcium channels to the ... Read more...


Mitochondrial Ca2+ cycling facilitates activation of the transcription factor NFAT in sensory neurons.

28 Sep 2009 Ca(2+)-dependent gene regulation controls many aspects of neuronal plasticity. Significant progress has been made toward understanding the roles of voltage- and ligand-gated Ca(2+) channels in triggering specific transcriptional responses. In ... Read more...

 

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Technical information about 'Calcium Signaling'

Definition: Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.

Descriptor UI: D020013

Alternative terms: Calcium Signaling; Calcium Signalings; Signaling, Calcium; Signalings, Calcium; Calcium Spikes; Calcium Spike; Spike, Calcium; Spikes, Calcium; Calcium Waves; Calcium Wave; Wave, Calcium; Waves, Calcium; Calcium Oscillations; Calcium Oscillation; Oscillation, Calcium; Oscillations, Calcium; Calcium Puffs; Calcium Puff; Puff, Calcium; Puffs, Calcium;

Related Mesh Headings: Calmodulin; Calcium Channels; Inositol 1,4,5-Trisphosphate;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G02.111.087.800.800.100; G02.149.115.800.800.100; G03.495.166.500.100; G04.299.880.800.100;

History Note: 99

Technical Notes: calcium mobilization in context of signal transduction goes here, in other cases index CALCIUM/metab

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