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Calcium Signaling
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Definition of 'Calcium Signaling'

Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.

Common names: Calcium Signaling; Calcium Signalings; Signaling, Calcium; Signalings, Calcium; Calcium Spikes; Calcium Spike; Spike, Calcium; Spikes, Calcium; Calcium Waves; Calcium Wave; Wave, Calcium; Waves, Calcium; Calcium Oscillations; Calcium Oscillation; Oscillation, Calcium; Oscillations, Calcium

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Sunday, November 22, 2009

Odontoblast TRP channels and thermo/mechanical transmission.

30 Oct 2009 Odontoblasts function as mechanosensory receptors because of the expression of mechanosensitive channels in these cells. However, it is unclear if odontoblasts direct the signal transmission evoked by heat/cold or osmotic changes. This study ... Read more...


Navigating the leukocyte signaling maze guided by Ariadne's thread.

30 Oct 2009 Ariadne is the legendary Minoan goddess of the Labyrinth. The term 'Ariadne's thread' is used to describe the understanding of complex issues. Immunologists attending the 5th Leukocyte Signal Transduction Workshop discussed the Ariadne's thread ... Read more...


Negative regulation of endogenous protein kinase Calpha on the dynamic change of carbachol-induced intracellular calcium response in different melanoma cells.

30 Oct 2009 Regulations of intracellular protein kinase C (PKC) on carbachol (CCh)-induced intracellular calcium ([Ca(2+)]i) responses were investigated in different stages of melanoma cells. We found that CCh (1 mM) significantly increased [Ca(2+)]i with 6-, ... Read more...

 

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Technical information about 'Calcium Signaling'

Definition: Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.

Descriptor UI: D020013

Alternative terms: Calcium Signaling; Calcium Signalings; Signaling, Calcium; Signalings, Calcium; Calcium Spikes; Calcium Spike; Spike, Calcium; Spikes, Calcium; Calcium Waves; Calcium Wave; Wave, Calcium; Waves, Calcium; Calcium Oscillations; Calcium Oscillation; Oscillation, Calcium; Oscillations, Calcium; Calcium Puffs; Calcium Puff; Puff, Calcium; Puffs, Calcium;

Related Mesh Headings: Calmodulin; Calcium Channels; Inositol 1,4,5-Trisphosphate;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G02.111.087.800.800.100; G02.149.115.800.800.100; G03.495.166.500.100; G04.299.880.800.100;

History Note: 99

Technical Notes: calcium mobilization in context of signal transduction goes here, in other cases index CALCIUM/metab

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