Cannabidiol - Pharmacokinetics
Research News and Information

Sunday, November 22, 2009

Modulation of mediotemporal and ventrostriatal function in humans by Delta9-tetrahydrocannabinol: a neural basis for the effects of Cannabis sativa on learning and psychosis.

30 Mar 2009 CONTEXT: Cannabis sativa use can impair verbal learning, provoke acute psychosis, and increase the risk of schizophrenia. It is unclear where C. sativa acts in the human brain to modulate verbal learning and to induce psychotic symptoms. OBJECTIVES: ... Read more...

Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing.

30 Dec 2008 CONTEXT: Cannabis use can both increase and reduce anxiety in humans. The neurophysiological substrates of these effects are unknown. OBJECTIVE: To investigate the effects of 2 main psychoactive constituents of Cannabis sativa ... Read more...

Precipitation complexation method produces cannabidiol/beta-cyclodextrin inclusion complex suitable for sublingual administration of cannabidiol.

30 Jan 2007 In the present study, the precipitation complexation method was used to prepare a complex of cannabidiol (CBD) with beta-CD. The effect of beta-CD-complexation on the sublingual absorption of CBD was studied in rabbits. A solid CBD/beta-CD inclusion ... Read more...

Latest indexed articles for 'Cannabidiol - Pharmacokinetics'

These are the very latest articles for this heading:

• Modulation of mediotemporal and ventrostriatal function in humans by Delta9-tetrahydrocannabinol: a neural basis for the effects of Cannabis sativa on learning and psychosis. 30 Mar 2009
• Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing. 30 Dec 2008
• Precipitation complexation method produces cannabidiol/beta-cyclodextrin inclusion complex suitable for sublingual administration of cannabidiol. 30 Jan 2007
• Heterogeneity of human adipose blood flow. 18 Jan 2007
• Interactions between THC and cannabidiol in mouse models of cannabinoid activity. 28 Mar 2006
• Randomized, double-blind, placebo-controlled study about the effects of cannabidiol (CBD) on the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) after oral application of THC verses standardized cannabis extract. 29 Nov 2005
• Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential. 29 Apr 2005
• Pharmacokinetics and metabolism of the plant cannabinoids, delta9-tetrahydrocannabinol, cannabidiol and cannabinol. 30 Dec 2004
• Human skin permeation of Delta8-tetrahydrocannabinol, cannabidiol and cannabinol. 28 Feb 2004
• Controlled clinical trial of cannabidiol in Huntington's disease. 30 Oct 1991
• Comparative metabolism of cannabidiol in dog, rat and man. 30 Oct 1991
• Metabolism of cannabidiol by the rat. 29 Sep 1991
• Pharmacokinetics of urinary metabolites of cannabidiol in the dog. 29 Nov 1990
• Metabolites of cannabidiol identified in human urine. 27 Feb 1990
• Pharmacokinetics of the dimethylheptyl homolog of cannabidiol in dogs. 30 Oct 1988
• Pharmacokinetics of cannabidiol in dogs. 29 Apr 1988
• Pharmacokinetics and disposition of cannabinoids. 30 Dec 1986

See a longer list of these articles.

Technical information about 'Cannabidiol'

Definition: Compound isolated from Cannabis sativa extract.

Chemical name: 1,3-Benzenediol, 2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)-5-pentyl-, (1R-trans)-

Registry Number: 13956-29-1

Descriptor UI: D002185

Alternative terms: Cannabidiol;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.455.849.090.100;

History Note: 91(75); was see under CANNABINOIDS 1977-90; was see under CANNABIS 1975-76