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Carbamazepine
Research News and Information
Definition of 'Carbamazepine'An anticonvulsant used to control grand mal and psychomotor or focal seizures. Its mode of action is not fully understood, but some of its actions resemble those of PHENYTOIN; although there is little chemical resemblance between the two compounds, their three-dimensional structure is similar. Common names: Carbamazepine; Neurotol; Tegretol; Amizepine; Carbamazepine Acetate; Acetate, Carbamazepine; Epitol; Carbamazepine Hydrochloride; Hydrochloride, Carbamazepine; Carbamazepine L-Tartrate (4:1); Carbamazepine Phosphate; Phosphate, Carbamazepine; Carbamazepine Sulfate (2:1); Carbazepin; Finlepsin |
Saturday, November 21, 2009
29 Sep 2009 
BACKGROUND AND OBJECTIVE: Carbamazepine (CBZ) is metabolized mainly by the CYP3A family of enzymes, which includes CYP3A4 and CYP3A5. Several studies have suggested that the CYP3A5*3 genotype influences the pharmacokinetics of CYP3A substrates. The ... Read more...
Oxcarbazepine in combination with Tiaprid in inpatient alcohol-withdrawal--a RCT.
30 Aug 2009 INTRODUCTION: Oxcarbazepine (OXC), a derivative of Carbamazepine (CBZ), may represent a solution to metabolic and side effects of CBZ treatment due to the fact that renal excretion is its major route of elimination. The goal of the study is to ... Read more...
The use of antiepileptic drugs in pediatric brain tumor patients.
30 Aug 2009 Antiepileptic drugs are frequently used in children with brain tumors. This retrospective study reviewed chronic use of antiepileptic drugs in children with brain tumors at two children's hospitals between 2000 and 2007. Antiepileptic drugs were ... Read more...
Latest indexed articles for 'Carbamazepine'
These are the very latest articles for this heading:
- Effect of CYP3A5*3 genotype on serum carbamazepine concentrations at steady-state in Korean epileptic patients. 29 Sep 2009
- Oxcarbazepine in combination with Tiaprid in inpatient alcohol-withdrawal--a RCT. 30 Aug 2009
- The use of antiepileptic drugs in pediatric brain tumor patients. 30 Aug 2009
- The effect of oxcarbazepine on bone metabolism. 30 Aug 2009
- Neurocysticercosis in the infant of a pregnant mother with a tapeworm. 30 Aug 2009
- Pregnancy treatment guidelines: throwing the baby out with the bath water.
30 Aug 2009 - Fate of carbamazepine during water treatment. 13 Aug 2009
- Carbamazepine-induced hyperammonemia. 13 Aug 2009
- The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na(+) channel. 30 Jul 2009
- [Case of frontal lobe epilepsy with gelastic seizures induced by emotion] 30 Jul 2009
- Evaluation of silica monoliths in affinity microcolumns for high-throughput analysis of drug-protein interactions. 30 Jul 2009
- Drug-induced hypersensitivity syndrome with superficial granulomatous dermatitis--a novel finding. 30 Jul 2009
- Prospective study on long-term treatment with oxcarbazepine in pediatric epilepsy. 12 Jul 2009
- Effects of environmental concentrations of the antiepilectic drug carbamazepine on biomarkers and cAMP-mediated cell signaling in the mussel Mytilus galloprovincialis. 5 Jul 2009
- 1. Trigeminal neuralgia. 29 Jun 2009
- Digital neuropathy of the median and ulnar nerves caused by Dupuytren's contracture: Case report. 29 Jun 2009
- Genetic variants in microsomal epoxide hydrolase influence carbamazepine dosing. 29 Jun 2009
- Using ultraviolet absorbance and color to assess pharmaceutical oxidation during ozonation of wastewater. 29 Jun 2009
- [Improvement of peduncular hallucinosis by surgical resection and carbamazepin administration in a young patient with pineocytoma] 29 Jun 2009
- Heparin-induced thrombocytopenia in a nonthrombocytopenic patient with toxic epidermal necrolysis causing fatal outcome: is HIT still a HIT? 29 Jun 2009
See a longer list of these articles.
Technical information about 'Carbamazepine'
Definition: An anticonvulsant used to control grand mal and psychomotor or focal seizures. Its mode of action is not fully understood, but some of its actions resemble those of PHENYTOIN; although there is little chemical resemblance between the two compounds, their three-dimensional structure is similar.
Chemical name: 5H-Dibenz(b,f)azepine-5-carboxamide
Registry Number: 298-46-4
Descriptor UI: D002220
Alternative terms: Carbamazepine; Neurotol; Tegretol; Amizepine; Carbamazepine Acetate; Acetate, Carbamazepine; Epitol; Carbamazepine Hydrochloride; Hydrochloride, Carbamazepine; Carbamazepine L-Tartrate (4:1); Carbamazepine Phosphate; Phosphate, Carbamazepine; Carbamazepine Sulfate (2:1); Carbazepin; Finlepsin; Carbamazepine Dihydrate; Dihydrate, Carbamazepine;
Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Pharmacological Action: Analgesics, Non-Narcotic; Anticonvulsants; Antimanic Agents;
Tree Number: D03.494.240.127;
History Note: 72(68)