Carcinoma, Squamous Cell - Physiopathology
Research News and Information

Sunday, November 22, 2009

Smad4: gatekeeper gene in head and neck squamous cell carcinoma.

17 Oct 2009 Unchecked cell growth is a hallmark of cancer. During oncogenesis, cancerous cells become resistant to the TGF-beta signaling pathway that usually keeps cell growth in check. The role of a critical mediator of this pathway, Smad4, in head and neck ... Read more...

Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation.

17 Oct 2009 Smad4 is a central mediator of TGF-beta signaling, and its expression is downregulated or lost at the malignant stage in several cancer types. In this study, we found that Smad4 was frequently downregulated not only in human head and neck squamous ... Read more...

Expression of VEGF-C correlates with a poor prognosis based on analysis of prognostic factors in 73 patients with esophageal squamous cell carcinomas.

30 Jul 2009 OBJECTIVE: The purpose of this study was to specifically investigate the clinicopathological role of expression of vascular endothelial growth factor-C (VEGF-C) as well as the correlation with clinical outcomes in esophageal squamous cell carcinomas ... Read more...

Latest indexed articles for 'Carcinoma, Squamous Cell - Physiopathology'

These are the very latest articles for this heading:

• Smad4: gatekeeper gene in head and neck squamous cell carcinoma. 17 Oct 2009
• Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation. 17 Oct 2009
• Expression of VEGF-C correlates with a poor prognosis based on analysis of prognostic factors in 73 patients with esophageal squamous cell carcinomas. 30 Jul 2009
• Rehabilitation: long-term physical and functional changes following treatment. 30 Jul 2009
• Cross talk initiated by endothelial cells enhances migration and inhibits anoikis of squamous cell carcinoma cells through STAT3/Akt/ERK signaling. 30 May 2009
• HGF and c-Met participate in paracrine tumorigenic pathways in head and neck squamous cell cancer. 24 May 2009
• Cytoplasmic accumulation of activated leukocyte cell adhesion molecule is a predictor of disease progression and reduced survival in oral cancer patients. 29 Apr 2009
• Absence of somatic mutations of NEMO in keratoacanthoma. 28 Apr 2009
• Pneumonectomy in the seventh decade in a patient with a congenital uncorrected ventricular septal defect. Apr 2009
• Larynx preservation clinical trial design: key issues and recommendations--a consensus panel summary. 30 Mar 2009
• [Development of scar cancer after subtotal oesophagectomy for corrosive injury] 30 Mar 2009
• Screening for dysfunction to promote multidisciplinary intervention by using the University of Washington Quality of Life Questionnaire. 30 Mar 2009
• Activity and toxicity of paclitaxel in pretreated metastatic penile cancer patients. 30 Mar 2009
• Density and migration of mast cells in lip squamous cell carcinoma and actinic cheilitis. 30 Mar 2009
• MAPK activation is necessary to the apoptotic death of KB cells induced by the essential oil isolated from Artemisia iwayomogi. 15 Mar 2009
• Peroxiredoxin IV protects cells from radiation-induced apoptosis in head-and-neck squamous cell carcinoma. 13 Mar 2009
• Hypercalcemia complicating Marjolin's ulcer. 27 Feb 2009
• Oral cancer diagnosis by mechanical phenotyping. 15 Feb 2009
• Beavertail modification of the radial forearm free flap in base of tongue reconstruction: technique and functional outcomes. 30 Jan 2009
• Squamous cell carcinomas in 2 patients with diffuse scleroderma treated with mycophenolate mofetil. 30 Jan 2009

See a longer list of these articles.

Technical information about 'Carcinoma, Squamous Cell'

Definition: A carcinoma derived from stratified squamous epithelium. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)

Descriptor UI: D002294

Alternative terms: Carcinoma, Squamous Cell; Carcinomas, Squamous Cell; Squamous Cell Carcinomas; Squamous Cell Carcinoma; Carcinoma, Squamous; Carcinomas, Squamous; Squamous Carcinoma; Squamous Carcinomas; Carcinoma, Epidermoid; Carcinomas, Epidermoid; Epidermoid Carcinoma; Epidermoid Carcinomas; Carcinoma, Planocellular; Carcinomas, Planocellular; Planocellular Carcinoma; Planocellular Carcinomas;

Allowable Qualifiers: blood; blood supply; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; secondary; secretion; surgery; therapy; ultrastructure; urine; veterinary; ultrasonography; chemistry; virology;

Tree Number: C04.557.470.200.400; C04.557.470.700.400;

Online Note: use CARCINOMA, SQUAMOUS CELL to search CARCINOMA, EPIDERMOID 1966-80

History Note: 81; was CARCINOMA, EPIDERMOID 1963-80

Technical Notes: coordinate IM with precoordinated organ/neoplasm term (IM)