Catechols - Chemistry
Research News and Information

Monday, March 22, 2010

Two new phenylglycol derivatives isolated from Syringa reticulata var. mandshurica and their antifungal activities.

30 Jul 2009 Two new phenylglycol derivatives, (S)-(+)-2-(3,4-dihydroxy phenyl)-2-ethoxyl- ethanol and (S)-(+)-2-(3,4-dihydroxy phenyl)-2-acetoxy-ethanol, were isolated from the leaves of Syringa reticulata var. mandshurica, along with two known phenethylols, ... Read more...

Investigation of the pharmacophore space of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) NTPase/helicase by dihydroxychromone derivatives.

7 Jul 2009 Aryl diketoacids have been identified as the first SARS-CoV NTPase/helicase inhibitors with a distinct pharmacophore featuring an arylmethyl group attached to a diketoacid. In order to search for the pharmacophore space around the diketoacid core, ... Read more...

Protein reactivity of 3,4-dihydroxyphenylacetaldehyde, a toxic dopamine metabolite, is dependent on both the aldehyde and the catechol.

29 Jun 2009 Dopamine (DA) has been implicated as an endogenous neurotoxin to explain selective neurodegeneration, as observed for Parkinson's disease (PD). However, previous work demonstrated that 3,4-dihydroxyphenylacetaldehyde (DOPAL) was more toxic than DA. ... Read more...

Latest indexed articles for 'Catechols - Chemistry'

These are the very latest articles for this heading:

• Iron-substituted polyoxotungstates as inorganic synzymes: evidence for a biomimetic pathway in the catalytic oxygenation of catechols. 8 Aug 2009
• Two new phenylglycol derivatives isolated from Syringa reticulata var. mandshurica and their antifungal activities. 30 Jul 2009
• Investigation of the pharmacophore space of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) NTPase/helicase by dihydroxychromone derivatives. 7 Jul 2009
• Protein reactivity of 3,4-dihydroxyphenylacetaldehyde, a toxic dopamine metabolite, is dependent on both the aldehyde and the catechol. 29 Jun 2009
• Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes. 29 Jun 2009
• Synergetic effect of ultrasound with dual fields for the degradation of nitrobenzene in aqueous solution. 29 Jun 2009
• Vibriobactin antibodies: a vaccine strategy. 23 Jun 2009
• FerriBRIGHT: a rationally designed fluorescent probe for redox active metals. 22 Jun 2009
• Gas production in the bromate-pyrocatechol oscillator. 16 Jun 2009
• Enantioselectivity in the methylation of the catecholic phase I metabolites of methylenedioxy designer drugs and their capability to inhibit catechol-O-methyltransferase-catalyzed dopamine 3-methylation. 30 May 2009
• Diagnosis of treatment efficiency in industrial wastewater treatment plants: a case study at a refinery ETP. 13 May 2009
• Electrochemical sensor for catechol and dopamine based on a catalytic molecularly imprinted polymer-conducting polymer hybrid recognition element. 29 Apr 2009
• Synthesis and characterization of V(V)(3,6-DBSQ)(3,6-DBCat)2, a d(0) metal complex with dioxygenase catalytic activity. 18 Apr 2009
• A selective de-O-methylation of guaiacyl lignans to corresponding catechol derivatives by 2-iodoxybenzoic acid (IBX). The role of the catechol moiety on the toxicity of lignans. Apr 2009
• Molecular recognition and self-assembly special feature: A general protocol for creating high-throughput screening assays for reaction yield and enantiomeric excess applied to hydrobenzoin. 28 Mar 2009
• Adsorption behavior of uranium(VI) and other ionic species on cross-linked chitosan resins modified with chelating moieties. 24 Mar 2009
• An enantioselective synthesis of (+)-(S)-[n]-gingerols via the L-proline-catalyzed aldol reaction. 22 Mar 2009
• Oxidant activity of tris(2,4,6-trichloro-3,5-dinitrophenyl)methyl radical with catechol and pyrogallol. Mechanistic considerations. 18 Mar 2009
• Adsorption/electrosorption of catechol and resorcinol onto high area activated carbon cloth. 16 Mar 2009
• Catechol boronate formation and its electrochemical oxidation. 16 Mar 2009

See a longer list of these articles.

Technical information about 'Catechols'

Definition: A group of 1,2-benzenediols that contain the general formula R-C6H5O2.

Registry Number: 0

Descriptor UI: D002396

Alternative terms: Catechols; Pyrocatechols; o-Dihydroxybenzenes; o Dihydroxybenzenes; ortho-Dihydroxybenzenes; ortho Dihydroxybenzenes;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.755.166;

Online Note: use CATECHOLS to search CATECHOL 1966-74

History Note: 75; was CATECHOL 1963-74