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Cell Differentiation - Physiology
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Definition of 'Cell Differentiation'

Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.

Common names: Cell Differentiation; Differentiation, Cell; Cell Differentiations; Differentiations, Cell

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Saturday, November 21, 2009

p38 MAPK mediated in compressive stress-induced chondrogenesis of rat bone marrow MSCs in 3D alginate scaffolds.

29 Nov 2009 Mesenchymal stem cells (MSCs) are well known to have the capability to form bone and cartilage, and chondrogenesis derived from MSCs is reported to be affected by mechanical stimuli. This research was aimed to study the effects of cyclic compressive ... Read more...


Osteoblast differentiation is functionally associated with decreased AMP kinase activity.

29 Nov 2009 Osteoblasts, originating from mesenchymal stem cells, play a pivotal role in bone formation and mineralization. Several transcription factors including runt-related transcription factor 2 (Runx2) have been reported to be essential for osteoblast ... Read more...


Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling.

29 Nov 2009 The role of OxLDL in the generation and progression of atherosclerosis is well admitted. In addition, it is well known that atherosclerosis is often accompanied by perturbations in bone remodeling, resulting in osteoporosis. In the current studies, ... Read more...

 

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Technical information about 'Cell Differentiation'

Definition: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.

Descriptor UI: D002454

Alternative terms: Cell Differentiation; Differentiation, Cell; Cell Differentiations; Differentiations, Cell;

Related Mesh Headings: Antigens, Differentiation; Cell Lineage;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G04.299.151;

History Note: 66(64)

Technical Notes: coordinate with specific cell /cytol; not for micro-organisms; CELL DEDIFFERENTIATION and CELL TRANSDIFFERENTIATION are also available

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