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Cell Differentiation
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Definition of 'Cell Differentiation'

Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.

Common names: Cell Differentiation; Differentiation, Cell; Cell Differentiations; Differentiations, Cell

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Saturday, November 21, 2009

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

29 Nov 2009 Osteosarcomas are the most prevalent primary bone tumors found in pediatric patients. To understand their molecular etiology, cell culture models are used to define disease mechanisms under controlled conditions. Many osteosarcoma cell lines (e.g., ... Read more...


p38 MAPK mediated in compressive stress-induced chondrogenesis of rat bone marrow MSCs in 3D alginate scaffolds.

29 Nov 2009 Mesenchymal stem cells (MSCs) are well known to have the capability to form bone and cartilage, and chondrogenesis derived from MSCs is reported to be affected by mechanical stimuli. This research was aimed to study the effects of cyclic compressive ... Read more...


OPLA scaffold, collagen I, and horse serum induce an higher degree of myogenic differentiation of adult rat cardiac stem cells.

29 Nov 2009 In the last few years, a major goal of cardiac research has been to drive stem cell differentiation to replace damaged myocardium. Several research groups have attempted to differentiate potential cardiac stem cells (CSCs) using bi- or ... Read more...

 

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Technical information about 'Cell Differentiation'

Definition: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.

Descriptor UI: D002454

Alternative terms: Cell Differentiation; Differentiation, Cell; Cell Differentiations; Differentiations, Cell;

Related Mesh Headings: Antigens, Differentiation; Cell Lineage;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G04.299.151;

History Note: 66(64)

Technical Notes: coordinate with specific cell /cytol; not for micro-organisms; CELL DEDIFFERENTIATION and CELL TRANSDIFFERENTIATION are also available

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