Cell Polarity
Research News and Information

Sunday, November 22, 2009

Sphingosine kinase 2 deficient tumor xenografts show impaired growth and fail to polarize macrophages towards an anti-inflammatory phenotype.

30 Oct 2009 A challenging task of the immune system is to fight cancer cells. However, a variety of human cancers educate immune cells to become tumor supportive. This is exemplified for tumor-associated macrophages (TAMs), which are polarized towards an ... Read more...

Protein cytoskeleton and overexpression of Na(+),K(+)-ATPase in opossum kidney cells.

30 Oct 2009 Previous studies have shown that over time in culture opossum kidney (OK) cells are endowed with increased Na(+),K(+)-ATPase activity and expression (Silva et al., 2006, J Membr Biol 212:163-175; Silva and Soares-da-Silva, 2007, Am J Physiol Regul ... Read more...

Guidance receptors find their places in the axonal order.

27 Oct 2009 In this issue of Neuron, Katsuki and colleagues show that cell-autonomous mechanisms divide Drosophila axons into proximal and distal compartments. Axon guidance receptors selectively localize to one compartment. A diffusion barrier exists near the ... Read more...

Latest indexed articles for 'Cell Polarity'

These are the very latest articles for this heading:

• Sphingosine kinase 2 deficient tumor xenografts show impaired growth and fail to polarize macrophages towards an anti-inflammatory phenotype. 30 Oct 2009
• Protein cytoskeleton and overexpression of Na(+),K(+)-ATPase in opossum kidney cells. 30 Oct 2009
• Guidance receptors find their places in the axonal order. 27 Oct 2009
• Senthil Muthuswamy: a new road map for cancer. Interview by Caitlin Sedwick. 17 Oct 2009
• Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain. 14 Oct 2009
• The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse. 14 Oct 2009
• A view to a kill: how ligand quality controls lethal hits. 14 Oct 2009
• Sonic hedgehog regulates integrin activity, cadherin contacts, and cell polarity to orchestrate neural tube morphogenesis. 5 Oct 2009
• Cdc42 antagonizes Rho1 activity at adherens junctions to limit epithelial cell apical tension. 3 Oct 2009
• A bacterial virulence factor that dissipates tension. 29 Sep 2009
• Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo. 29 Sep 2009
• The cell adhesion molecules Echinoid and Friend of Echinoid coordinate cell adhesion and cell signaling to regulate the fidelity of ommatidial rotation in the Drosophila eye. 29 Sep 2009
• Atypical protein kinase C activity is required for extracellular matrix degradation and invasion by Src-transformed cells. 29 Sep 2009
• Silencing the SPCA1 (secretory pathway Ca2+-ATPase isoform 1) impairs Ca2+ homeostasis in the Golgi and disturbs neural polarity. 28 Sep 2009
• Coupled myosin VI motors facilitate unidirectional movement on an F-actin network. 26 Sep 2009
• Mechanisms of alveolar epithelial chloride absorption. 23 Sep 2009
• AnkyrinG is required to maintain axo-dendritic polarity in vivo. 22 Sep 2009
• The bacterial virulence factor InlC perturbs apical cell junctions and promotes cell-to-cell spread of Listeria. 18 Sep 2009
• The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. 18 Sep 2009
• Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells. 16 Sep 2009

See a longer list of these articles.

Technical information about 'Cell Polarity'

Definition: Orientation of intracellular structures especially with respect to the apical and basolateral domains of the plasma membrane. Polarized cells must direct proteins from the Golgi apparatus to the appropriate domain since tight junctions prevent proteins from diffusing between the two domains.

Descriptor UI: D016764

Alternative terms: Cell Polarity; Cell Polarities; Polarities, Cell; Polarity, Cell;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G04.180;

History Note: 92

Technical Notes: orientation of intracell struct to plasma membrane