Cell Proliferation
Research News and Information

Saturday, November 21, 2009

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

29 Nov 2009 Osteosarcomas are the most prevalent primary bone tumors found in pediatric patients. To understand their molecular etiology, cell culture models are used to define disease mechanisms under controlled conditions. Many osteosarcoma cell lines (e.g., ... Read more...

Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.

29 Nov 2009 The expression profile and functions of the brain-enriched Rab22B/Rab31 small GTPase had remained uncharacterized. Using specific antibodies against Rab22B, we found the protein to be exceptionally enriched in nestin and RC2-positive radial glia of ... Read more...

Ceramide metabolism determines glioma cell resistance to chemotherapy.

29 Nov 2009 Tumor cell resistance to chemotherapy constitutes a major problem in the treatment of malignant tumors. We here investigated the role of ceramide metabolism for the resistance of glioma cells to treatment with the chemotherapeutic drug, gemcitabine. ... Read more...

Latest indexed articles for 'Cell Proliferation'

These are the very latest articles for this heading:

• Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1). 29 Nov 2009
• Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells. 29 Nov 2009
• Ceramide metabolism determines glioma cell resistance to chemotherapy. 29 Nov 2009
• Kinetics of transport and phosphorylation of glucose in cancer cells. 29 Nov 2009
• Growth inhibition of bovine pulmonary artery smooth muscle cells following long-term heparin treatment. 29 Nov 2009
• p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage. 29 Nov 2009
• Protein kinase C alpha-dependent signaling mediates endometrial cancer cell growth and tumorigenesis. 29 Nov 2009
• Cell cycle-related kinase supports ovarian carcinoma cell proliferation via regulation of cyclin D1 and is a predictor of outcome in patients with ovarian carcinoma. 29 Nov 2009
• RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells. 29 Nov 2009
• Prostaglandin E(2) promotes cell proliferation via protein kinase C/extracellular signal regulated kinase pathway-dependent induction of c-Myc expression in human esophageal squamous cell carcinoma cells. 29 Nov 2009
• Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model. 29 Nov 2009
• Annexin-A7 protects normal prostate cells and induces distinct patterns of RB-associated cytotoxicity in androgen-sensitive and -resistant prostate cancer cells. 29 Nov 2009
• Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1. 29 Nov 2009
• Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway. 29 Nov 2009
• Continuous and intermittent dosing of lonafarnib potentiates the therapeutic efficacy of docetaxel on preclinical human prostate cancer models. 29 Nov 2009
• HER3 is required for the maintenance of neuregulin-dependent and -independent attributes of malignant progression in prostate cancer cells. 29 Nov 2009
• Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate cancer to docetaxel. 29 Nov 2009
• Role of Wnt inhibitory factor-1 and Wnt/wingless signaling in choroid plexus tumors. 29 Nov 2009
• The reduction of cell death and proliferation by p27(Kip1) minimizes DNA damage in an experimental model of genotoxicity. 13 Nov 2009
• Restriction of cisplatin induction of acute apoptosis to a subpopulation of cells in a three-dimensional carcinoma culture model. 13 Nov 2009

See a longer list of these articles.

Technical information about 'Cell Proliferation'

Definition: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.

Descriptor UI: D049109

Alternative terms: Cell Proliferation; Proliferation, Cell; Cellular Proliferation; Proliferation, Cellular; Cell Multiplication; Multiplication, Cell; Cell Growth in Number; Cell Number Growth; Growth, Cell Number; Number Growth, Cell;

Related Mesh Headings: Hyperplasia;

Allowable Qualifiers: drug effects; radiation effects; ethics;

Tree Number: G04.299.233.750; G07.700.320.249.410.750;

History Note: 2005