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Cell Survival - Radiation effects
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Definition of 'Cell Survival'

The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.

Common names: Cell Survival; Survival, Cell; Cell Viability; Cell Viabilities; Viabilities, Cell; Viability, Cell

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Sunday, November 22, 2009

Validation of temporal optimization effects for a single fraction of radiation in vitro.

13 Nov 2009 PURPOSE: To experimentally validate how temporal modification of the applied dose pattern within a single fraction of radiation therapy affects cell survival. METHOD AND MATERIALS: Using the linear-quadratic model, we have previously demonstrated ... Read more...


The PPARalpha agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation.

30 Oct 2009 PURPOSE: Whole-brain irradiation (WBI) leads to cognitive impairment months to years after radiation. Numerous studies suggest that decreased hippocampal neurogenesis and microglial activation are involved in the pathogenesis of WBI-induced brain ... Read more...


Photodynamic treatment of culture medium containing serum induces long-lasting toxicity in vitro.

29 Sep 2009 Photodynamic therapy (PDT) produces singlet oxygen and reactive oxygen species (ROS) that damage tumor cells and the vasculature. The resulting effect is a balance between photo-oxidations through primary or secondary ROS and scavenging activity. ... Read more...

 

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Technical information about 'Cell Survival'

Definition: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.

Descriptor UI: D002470

Alternative terms: Cell Survival; Survival, Cell; Cell Viability; Cell Viabilities; Viabilities, Cell; Viability, Cell;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G04.299.316;

History Note: 76(71); was see under CYTOLOGY 1975

Technical Notes: NIM; not for micro-organisms

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