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Central Nervous System Depressants - Blood
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Definition of 'Central Nervous System Depressants'

A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).

Common names: Central Nervous System Depressants; CNS Depressants; Depressants, CNS

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Sunday, November 22, 2009

Chronic ethanol treatment potentiates ethanol-induced increases in interstitial nucleus accumbens endocannabinoid levels in rats.

21 Jul 2009 We employed in vivo microdialysis to characterize the effect of an ethanol challenge injection on endocannabinoid levels in the nucleus accumbens of ethanol-naïve and chronic ethanol-treated rats. Ethanol (0.75 and 2 g/kg, i.p.) dose-dependently ... Read more...


Alcohol intoxication requiring hospital admission in children and adolescents: retrospective analysis at the University Children's Hospital in the Slovak Republic.

29 Jun 2009 BACKGROUND: Few epidemiological studies have investigated the problem of children and adolescents taken to hospital with acute alcohol intoxication. METHODS: We reviewed the medical records of children and adolescents aged Read more...


Short-term alcohol administration alters KiSS-1 gene expression in the reproductive hypothalamus of prepubertal female rats.

8 Jun 2009 BACKGROUND: Kisspeptins bind to the G-protein-coupled receptor (GPR54) to activate hypothalamic luteinizing hormone releasing hormone (LHRH) secretion at the time of puberty. Alcohol (ALC) causes depressed prepubertal LHRH release, resulting in ... Read more...

 

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Technical information about 'Central Nervous System Depressants'

Definition: A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).

Registry Number: 0

Descriptor UI: D002492

Alternative terms: Central Nervous System Depressants; CNS Depressants; Depressants, CNS;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.277; D27.505.954.427.210;

Online Note: consider also CENTRAL NERVOUS SYSTEM /DE + DEPRESSION, CHEMICAL or BRAIN /DE + DEPRESSION, CHEMICAL

History Note: 79; was NON MESH before 1979

Technical Notes: GEN or unspecified; prefer specific groups or specific drugs; consider also CENTRAL NERVOUS SYSTEM /drug eff or BRAIN /drug eff; DF: CNS DEPRESS

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