Central Nervous System Depressants
Research News and Information

Sunday, November 22, 2009

Deficits in substance P mRNA levels in the CeA are inversely associated with alcohol-motivated responding.

30 Oct 2009 In the present study, in vitro and in vivo studies were conducted to determine the relationship between innate substance P (SP) levels and alcohol-motivated behavior in alcohol-preferring (P) and nonpreferring (NP) rat lines. In Experiment 1, in ... Read more...

[Circadian rhythm sleep disorders]

22 Sep 2009 BACKGROUND: Circadian rhythm sleep disorders often lead to sleepiness and insomnia. These disorders are characterized by a misalignment between the intrinsic circadian rhythm and the external social and physical environment. MATERIAL AND METHOD: ... Read more...

Ethanol induces apoptosis in human mast cells.

18 Sep 2009 AIMS: Alcohol abuse is associated with increased frequency of infections attributed to ethanol-induced immune suppression. The precise mechanism of immune suppression is however not known. Mast cells (MC) belong to the innate immune system and they ... Read more...

Latest indexed articles for 'Central Nervous System Depressants'

These are the very latest articles for this heading:

• Deficits in substance P mRNA levels in the CeA are inversely associated with alcohol-motivated responding. 30 Oct 2009
• [Circadian rhythm sleep disorders] 22 Sep 2009
• Ethanol induces apoptosis in human mast cells. 18 Sep 2009
• The effects of prenatal alcohol exposure on the morphological characteristics of spinal motoneurons. 30 Aug 2009
• Self-report of alcohol use for pain in a multi-ethnic community sample. 30 Aug 2009
• Lethal poisoning with ethiofencarb and ethanol. 30 Aug 2009
• Laterality of cortical response to ethanol is moderated by TaqIA A1 allele. 30 Aug 2009
• Essential involvement of the NMDA receptor in ethanol preconditioning-dependent neuroprotection from amyloid-betain vitro. 17 Aug 2009
• GABA(B) receptors, schizophrenia and sleep dysfunction: a review of the relationship and its potential clinical and therapeutic implications. 30 Jul 2009
• The effects of energy drinks alone and with alcohol on neuropsychological functioning. 30 Jul 2009
• Naloxone decreases the inhibitory effect of ethanol on the release of arginine-vasopressin induced by physical exercise in man. 30 Jul 2009
• Chronic ethanol intake alters circadian phase shifting and free-running period in mice. 30 Jul 2009
• Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbens. 27 Jul 2009
• Ethanol affects transforming growth factor beta1-initiated signals: cross-talking pathways in the developing rat cerebral wall. 27 Jul 2009
• Chronic ethanol treatment potentiates ethanol-induced increases in interstitial nucleus accumbens endocannabinoid levels in rats. 21 Jul 2009
• Gastroprotective effect of lupeol on ethanol-induced gastric damage and the underlying mechanism. 14 Jul 2009
• Use of transdermal melatonin delivery to improve sleep maintenance during daytime. 13 Jul 2009
• Alcohol as a risk factor for pancreatitis. A systematic review and meta-analysis. 4 Jul 2009
• Increased apoptosis and reduced neuronal and glial densities in the hippocampus due to nicotine and ethanol exposure in adolescent mice. 29 Jun 2009
• [Dependence of atropin-induced amnesia fluctuations on the state of pineal gland] 29 Jun 2009

See a longer list of these articles.

Technical information about 'Central Nervous System Depressants'

Definition: A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).

Registry Number: 0

Descriptor UI: D002492

Alternative terms: Central Nervous System Depressants; CNS Depressants; Depressants, CNS;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.277; D27.505.954.427.210;

Online Note: consider also CENTRAL NERVOUS SYSTEM /DE + DEPRESSION, CHEMICAL or BRAIN /DE + DEPRESSION, CHEMICAL

History Note: 79; was NON MESH before 1979

Technical Notes: GEN or unspecified; prefer specific groups or specific drugs; consider also CENTRAL NERVOUS SYSTEM /drug eff or BRAIN /drug eff; DF: CNS DEPRESS