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Central Nervous System Stimulants - Chemistry
Research News and Information
Definition of 'Central Nervous System Stimulants'A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. Common names: Central Nervous System Stimulants; Central Stimulants; Stimulants, Central; Analeptics; Analeptic Drugs; Drugs, Analeptic; Analeptic Agents; Agents, Analeptic |
Sunday, November 22, 2009
Clinical implications of chirality and stereochemistry in psychopharmacology.
30 Jul 2009 
Chirality, the concept of nonsuperimposable mirror images, is a fundamental property of biological systems and can be observed on a molecular, cellular, or organism level. Stereoisomer compounds possess the same molecular and structural formula, but ... Read more...
LC-MS of novel narcoepileptics and related substances.
29 Apr 2009 Modafinil, adrafinil and their related substances were synthesized and analyzed by RP-LC with ESI-MS/MS. The ionization mode, polarity, cone voltage, and chromatographic conditions were evaluated. The optimum LC-MS conditions to obtain fragment ions ... Read more...
Juvenile methylphenidate exposure and factors that influence incentive processing.
15 Apr 2009 Methylphenidate (MPH) is one of the few psychotropic agents approved for use in pediatric populations, underscoring the importance of elucidating any long-term consequences following exposure to this agent. Here, we examined the influence of several ... Read more...
Latest indexed articles for 'Central Nervous System Stimulants - Chemistry'
These are the very latest articles for this heading:
- Clinical implications of chirality and stereochemistry in psychopharmacology. 30 Jul 2009
- LC-MS of novel narcoepileptics and related substances. 29 Apr 2009
- [Drugs and desperation in different worlds. Abuse of cathinone and methcathinone]
29 Apr 2009 - Juvenile methylphenidate exposure and factors that influence incentive processing. 15 Apr 2009
- Impact of US and Canadian precursor regulation on methamphetamine purity in the United States. 27 Feb 2009
- Prodrugs of thyrotropin-releasing hormone and related peptides as central nervous system agents. 4 Feb 2009
- Oxethazaine as the source of mephentermine and phentermine in athlete's urine. 18 Jan 2009
- Comparison of steady-state plasma concentrations of armodafinil and modafinil late in the day following morning administration: post hoc analysis of two randomized, double-blind, placebo-controlled, multiple-dose studies in healthy male subjects. 30 Dec 2008
- ToF-SIMS application in the visualization and analysis of fingerprints after contact with amphetamine drugs. 21 Dec 2008
- Efficient synthesis and biological evaluation of two modafinil analogues. 15 Oct 2008
- Developmental toxicity assessment of d,l-methylphenidate and d-methylphenidate in rats and rabbits. 29 Sep 2008
- Scale-up studies on high shear wet granulation process from mini-scale to commercial scale.
29 Sep 2008 - Implementation of gas chromatography combined with simultaneously selected ion monitoring and full scan mass spectrometry in doping analysis. 17 Sep 2008
- Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis. 13 May 2008
- Armodafinil: a new treatment for excessive sleepiness. 30 Mar 2008
- Evaluation of characteristic deuterium distributions of ephedrines and methamphetamines by NMR spectroscopy for drug profiling. 13 Feb 2008
- Quality control of multi-component, intact pharmaceutical tablets with three different near-infrared apparatuses. 30 Dec 2007
- Dopamine/serotonin releasers as medications for stimulant addictions. 30 Dec 2007
- Histamine H3 antagonists as wake-promoting and pro-cognitive agents. 30 Dec 2007
- School-based administration of ADHD drugs decline, along with diversion, theft, and misuse. 29 Nov 2007
See a longer list of these articles.
Technical information about 'Central Nervous System Stimulants'
Definition: A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.
Registry Number: 0
Descriptor UI: D000697
Alternative terms: Central Nervous System Stimulants; Central Stimulants; Stimulants, Central; Analeptics; Analeptic Drugs; Drugs, Analeptic; Analeptic Agents; Agents, Analeptic;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D27.505.696.282; D27.505.954.427.220;
Online Note: use CENTRAL NERVOUS SYSTEM STIMULANTS to search ANALEPTICS 1966-94
History Note: 95; was ANALEPTICS 1963-94; CENTRAL NERVOUS SYSTEM STIMULANTS was see ANALEPTICS 1985-94
Technical Notes: GEN or unspecified; prefer specifics; consider also CENTRAL NERVOUS SYSTEM /drug eff & BRAIN /drug eff; DF: CNS STIMULANTS