Central Nervous System Stimulants - Pharmacology
Research News and Information

Saturday, November 21, 2009

Endocannabinoid modulation of amphetamine sensitization is disrupted in a rodent model of lesion-induced dopamine dysregulation.

30 Oct 2009 We tested the hypothesis that increased dopaminergic sensitivity induced by olfactory bulbectomy is mediated by dysregulation of endocannabinoid signaling. Bilateral olfactory bulbectomy induces behavioral and neurobiological symptomatology related ... Read more...

Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands.

21 Oct 2009 TAARs (trace amine-associated receptors) are G-protein-coupled receptors that respond to low abundance, endogenous amines such as tyramine and tryptamine, and represent potential targets for neuropsychiatric diseases. However, some members of this ... Read more...

Amphetamine and environmentally induced hyperthermia differentially alter the expression of genes regulating vascular tone and angiogenesis in the meninges and associated vasculature.

29 Sep 2009 An amphetamine (AMPH) regimen that does not produce a prominent blood-brain barrier breakdown was shown to significantly alter the expression of genes regulating vascular tone, immune function, and angiogenesis in vasculature associated with ... Read more...

Latest indexed articles for 'Central Nervous System Stimulants - Pharmacology'

These are the very latest articles for this heading:

• Endocannabinoid modulation of amphetamine sensitization is disrupted in a rodent model of lesion-induced dopamine dysregulation. 30 Oct 2009
• Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands. 21 Oct 2009
• Age-related changes in motor subtle signs among girls and boys with ADHD. 11 Oct 2009
• Amphetamine and environmentally induced hyperthermia differentially alter the expression of genes regulating vascular tone and angiogenesis in the meninges and associated vasculature. 29 Sep 2009
• Similar neurons, opposite adaptations: psychostimulant experience differentially alters firing properties in accumbens core versus shell. 28 Sep 2009
• [Neuroenhancement: doping for the brain] 27 Sep 2009
• An FMRI study of the effects of psychostimulants on default-mode processing during Stroop task performance in youths with ADHD. 13 Sep 2009
• [Basic sleep mechanisms] 8 Sep 2009
• Armodafinil. 30 Aug 2009
• Caffeine expectancy: instrument development in the Rasch measurement framework. 30 Aug 2009
• DNA-based MRI probes for specific detection of chronic exposure to amphetamine in living brains. 24 Aug 2009
• Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats. 16 Aug 2009
• The neurokinin-1 receptor modulates the methamphetamine-induced striatal apoptosis and nitric oxide formation in mice. 11 Aug 2009
• Caffeine enhances cognitive function and skill performance during simulated soccer activity. 30 Jul 2009
• Clinical implications of chirality and stereochemistry in psychopharmacology. 30 Jul 2009
• The effects of energy drinks alone and with alcohol on neuropsychological functioning. 30 Jul 2009
• Axotomy depletes intracellular calcium stores in primary sensory neurons. 30 Jul 2009
• Dopamine D2High receptors stimulated by phencyclidines, lysergic acid diethylamide, salvinorin A, and modafinil. 30 Jul 2009
• Fast oscillations in cortical-striatal networks switch frequency following rewarding events and stimulant drugs. 29 Jul 2009
• Disagreements with implications: diverging discourses on the ethics of non-medical use of methylphenidate for performance enhancement. 4 Jul 2009

See a longer list of these articles.

Technical information about 'Central Nervous System Stimulants'

Definition: A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.

Registry Number: 0

Descriptor UI: D000697

Alternative terms: Central Nervous System Stimulants; Central Stimulants; Stimulants, Central; Analeptics; Analeptic Drugs; Drugs, Analeptic; Analeptic Agents; Agents, Analeptic;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.282; D27.505.954.427.220;

Online Note: use CENTRAL NERVOUS SYSTEM STIMULANTS to search ANALEPTICS 1966-94

History Note: 95; was ANALEPTICS 1963-94; CENTRAL NERVOUS SYSTEM STIMULANTS was see ANALEPTICS 1985-94

Technical Notes: GEN or unspecified; prefer specifics; consider also CENTRAL NERVOUS SYSTEM /drug eff & BRAIN /drug eff; DF: CNS STIMULANTS