Chemistry, Pharmaceutical
Research News and Information

Sunday, November 22, 2009

Bioavailability of oral vitamin E formulations in adult volunteers and children with chronic cholestasis or cystic fibrosis.

29 Sep 2009 PURPOSE: To test bioequivalence of oral vitamin E formulations, water-soluble tocofersolan (test) and water-miscible (reference), in healthy adult volunteers, and their bioavailability in children with chronic cholestasis or cystic fibrosis. ... Read more...

Two different approaches for the prediction of in vivo plasma concentration-time profile from in vitro release data of once daily formulations of diltiazem hydrochloride.

24 Sep 2009 The aim of this study was to employ two different mathematical approaches: first, a convolution approach using computer software; second, a mathematical calculation exploiting Wagner-Nelson calculation to predict in vivo plasma concentration-time ... Read more...

Three periods of drying of a single square capillary tube.

14 Sep 2009 The drying kinetics of a porous medium is classically described in three main periods, which depend on the interplay between the external and internal mass transfers during evaporation. The first period is described as essentially depending on the ... Read more...

Latest indexed articles for 'Chemistry, Pharmaceutical'

These are the very latest articles for this heading:

• Bioavailability of oral vitamin E formulations in adult volunteers and children with chronic cholestasis or cystic fibrosis. 29 Sep 2009
• Two different approaches for the prediction of in vivo plasma concentration-time profile from in vitro release data of once daily formulations of diltiazem hydrochloride. 24 Sep 2009
• 2009 Claude S. Hudson Award in Carbohydrate Chemistry. Carbohydrates: a frontier in medicinal chemistry. 22 Sep 2009
• Three periods of drying of a single square capillary tube. 14 Sep 2009
• [The German interdisciplinary taskforce for clinical hemotherapy IAKH and its national critical incident reporting system specifically for blood transfusion] 9 Sep 2009
• Impact of opioid rescue medication for breakthrough pain on the efficacy and tolerability of long-acting opioids in patients with chronic non-malignant pain. 4 Sep 2009
• Compatibility of levofloxacin injection and magnesium sulfate. 30 Aug 2009
• Emerging drugs for the treatment of ulcerative colitis. 30 Aug 2009
• The case for open-access chemical biology. A strategy for pre-competitive medicinal chemistry to promote drug discovery. 30 Aug 2009
• Statistical evaluation of influence of polymers concentration on disintegration time and diazepam release from quick-disintegrating rapid release tablet. 30 Aug 2009
• In vitro method to characterize diffusion of dye from polymeric particles: a model for drug release. 30 Aug 2009
• Deuterated therapeutics: forensic toxicology consequences. 30 Aug 2009
• Synthesis of a quaternary bis derivative of imipramine as a novel compound with potential anti-enuretic effect. 30 Aug 2009
• Assessment methods of inhaled aerosols: technical aspects and applications. 30 Aug 2009
• Characterization of the behavior of alginate-based microcapsules in vitro and in vivo. 30 Aug 2009
• Current status of amorphous formulation and other special dosage forms as formulations for early clinical phases. 30 Aug 2009
• Professor Michael J. Pikal: scientist, family man, educator, colleague and friend. 30 Aug 2009
• Local mobility in amorphous pharmaceuticals--characterization and implications on stability. 30 Aug 2009
• Assay of diffusion of different botulinum neurotoxin type a formulations injected in the mouse leg. 30 Aug 2009
• Prothrombin complex concentrate and fatal thrombosis: poor evidence to implicate a relatively safe drug. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Chemistry, Pharmaceutical'

Definition: Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.

Descriptor UI: D002626

Alternative terms: Chemistry, Pharmaceutical; Pharmaceutical Chemistry; Pharmaceutic Chemistry; Chemistry, Pharmaceutic; Medicinal Chemistry; Chemistry, Medicinal; Drug Formulation; Drug Formulations; Formulation, Drug; Formulations, Drug;

Related Mesh Headings: Biopharmaceutics; Drug Compounding;

Allowable Qualifiers: classification; economics; education; history; instrumentation; legislation & jurisprudence; manpower; methods; organization & administration; standards; trends; statistics & numerical data; ethics;

Tree Number: H01.158.703.007; H01.181.466;

Technical Notes: use for the specialty and as an NIM coordinate; Manual 29.7; do not confuse the entry term DRUG FORMULATION with DRUG COMPOUNDING; DF: CHEM PHARM