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Cholesterol - Genetics
Research News and Information
Definition of 'Cholesterol'The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. Common names: Cholesterol; Epicholesterol |
Monday, November 23, 2009
3 Aug 2009 
Leukotriene (LT) B(4) is generated in response to engagement of the Fc gamma receptor (Fc gamma R) and potently contributes to Fc gamma R-mediated antimicrobial functions in pulmonary alveolar macrophages. In this study, we report that the LTB(4) ... Read more...
6 Jul 2009 Gaucher disease causes pathologic skeletal changes that are not fully explained. Considering the important role of mesenchymal stromal cells (MSCs) in bone structural development and maintenance, we analyzed the cellular biochemistry of MSCs from an ... Read more...
Cholesterol-modifying strategies for Alzheimer's disease.
29 Apr 2009 The link between cholesterol and Alzheimer's disease (AD) is indicated by genetic, epidemiological, experimental and clinical evidence, although the relationship is far from simple or straightforward. Compared with extracerebral cholesterol, little ... Read more...
Latest indexed articles for 'Cholesterol - Genetics'
These are the very latest articles for this heading:
- Evolution and cholesterol.
15 Aug 2009 - FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions. 3 Aug 2009
- Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome. 6 Jul 2009
- Cholesterol-modifying strategies for Alzheimer's disease. 29 Apr 2009
- Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detection. 30 Mar 2009
- Inhibitory effects of grape seed procyanidins on foam cell formation in vitro. 23 Mar 2009
- CYP46A1 variants influence Alzheimer's disease risk and brain cholesterol metabolism. 14 Mar 2009
- Differential regulation of the STARD1 subfamily of START lipid trafficking proteins in human macrophages. 8 Mar 2009
- Genetic and environmental influences on serum lipids and the effects of puberty: a Chinese twin study. 7 Mar 2009
- Transcriptome profiling analysis reveals multiple modulatory effects of Ginkgo biloba extract in the liver of rats on a high-fat diet. 27 Feb 2009
- A-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs.
15 Feb 2009 - Controversies in familial hypercholesterolaemia: recommendations of the NICE Guideline Development Group for the identification and management of familial hypercholesterolaemia. 21 Jan 2009
- LIPE C-60G influences the effects of physical activity on body fat and plasma lipid concentrations: the Quebec Family Study. 30 Dec 2008
- Peroxisome deficiency causes a complex phenotype because of hepatic SREBP/Insig dysregulation associated with endoplasmic reticulum stress. 22 Dec 2008
- Human SA gene polymorphisms are associated with non-high-density lipoprotein cholesterol in postmenopausal women: a pilot study. 21 Dec 2008
- Renal ischemia-induced cholesterol loading: transcription factor recruitment and chromatin remodeling along the HMG CoA reductase gene. 16 Dec 2008
- Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts. 10 Dec 2008
- Differing effect of protein isolates from different cultivars of blue lupin on plasma lipoproteins of hypercholesterolemic rats. 5 Dec 2008
- Nuclear SREBP-1a causes loss of pancreatic beta-cells and impaired insulin secretion. Dec 2008
- Glycosphingolipid deficiency increases the sterol regulatory element-mediated gene transcription. 15 Nov 2008
See a longer list of these articles.
Technical information about 'Cholesterol'
Definition: The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Chemical name: Cholest-5-en-3-ol (3beta)-
Registry Number: 57-88-5
Descriptor UI: D002784
Alternative terms: Cholesterol; Epicholesterol;
Related Mesh Headings: Hypercholesterolemia; Embolism, Cholesterol;
Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D04.808.247.222.284; D04.808.247.808.197; D10.570.938.208; D10.851.208;
Online Note: use CHOLESTEROL to search BLOOD CHOLESTEROL 1966-67
History Note: /blood was BLOOD CHOLESTEROL 1963-67
Technical Notes: GEN or unspecified; prefer specifics; /biosyn /physiol permitted; /blood: consider also HYPERCHOLESTEROLEMIA & specifics; cholesterol granuloma = CHOLESTEROL + GRANULOMA, FOREIGN-BODY