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Cholesterol - Metabolism
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Definition of 'Cholesterol'

The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.

Common names: Cholesterol; Epicholesterol

More technical Information...

Tuesday, November 24, 2009

Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice.

29 Sep 2009 Scavenger receptor class B type I (SR-BI) mediates selective uptake of cholesterol from high-density lipoprotein (HDL) particles by the liver and influences biliary cholesterol secretion. However, it is not clear, if this effect is direct or ... Read more...


Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha.

29 Sep 2009 Alcoholic steatosis is a fundamental metabolic disorder in the progression of alcoholic liver disease. Zinc deficiency is one of the most consistently observed biochemical/nutritional manifestations of alcoholic liver disease. The purpose of this ... Read more...


A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men.

22 Sep 2009 BACKGROUND: Osteoprotegerin (OPG) has been associated with cardiovascular events but currently the mechanisms underlying this association are unknown. OPG is thought to play a role in controlling artery calcification and small studies have suggested ... Read more...

 

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Technical information about 'Cholesterol'

Definition: The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.

Chemical name: Cholest-5-en-3-ol (3beta)-

Registry Number: 57-88-5

Descriptor UI: D002784

Alternative terms: Cholesterol; Epicholesterol;

Related Mesh Headings: Hypercholesterolemia; Embolism, Cholesterol;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D04.808.247.222.284; D04.808.247.808.197; D10.570.938.208; D10.851.208;

Online Note: use CHOLESTEROL to search BLOOD CHOLESTEROL 1966-67

History Note: /blood was BLOOD CHOLESTEROL 1963-67

Technical Notes: GEN or unspecified; prefer specifics; /biosyn /physiol permitted; /blood: consider also HYPERCHOLESTEROLEMIA & specifics; cholesterol granuloma = CHOLESTEROL + GRANULOMA, FOREIGN-BODY

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