Choline
Research News and Information

Monday, November 23, 2009

Application of high-resolution 1H MAS NMR spectroscopy to the analysis of intact bones from mice exposed to gamma radiation.

30 Oct 2009 Herein we demonstrate that high-resolution magic angle spinning (MAS) 1H NMR can be used to profile the pathology of bone marrow rapidly and with minimal sample preparation. The spectral resolution obtained allows several metabolites to be analyzed ... Read more...

Detection of aggressive primary prostate cancer with 11C-choline PET/CT using multimodality fusion techniques.

14 Sep 2009 The aim of the study was to assess whether (11)C-choline PET/CT could identify high-risk primary adenocarcinoma of the prostate. METHODS: (11)C-choline PET/CT and transpelvic MRI were performed in 14 patients with untreated localized primary ... Read more...

Teaching the modes of Ca2+ transport between the plasma membrane and endoplasmic reticulum using a classic paper by Kwan et al.

30 Aug 2009 This teaching article uses the report by Kwan et al., "Effects of methacholine, thapsigargin, and La(3+) on plasmalemmal and intracellular Ca(2+) transport in lacrimal acinar cells," where the effects of Ca(2+)-mobilizing agents in regulating Ca(2+) ... Read more...

Latest indexed articles for 'Choline'

These are the very latest articles for this heading:

• Application of high-resolution 1H MAS NMR spectroscopy to the analysis of intact bones from mice exposed to gamma radiation. 30 Oct 2009
• Detection of aggressive primary prostate cancer with 11C-choline PET/CT using multimodality fusion techniques. 14 Sep 2009
• Teaching the modes of Ca2+ transport between the plasma membrane and endoplasmic reticulum using a classic paper by Kwan et al. 30 Aug 2009
• Effects of overnight sleep restriction on brain chemistry and mood in women with unipolar depression and healthy controls. 30 Aug 2009
• Prolonged neurologic course of familial hemophagocytic lymphohistiocytosis. 30 Aug 2009
• (1)H spectroscopic imaging of human brain at 3 Tesla: comparison of fast three-dimensional magnetic resonance spectroscopic imaging techniques. 30 Aug 2009
• Dynamic MRI and CAD vs. choline MRS: where is the detection level for a lesion characterisation in prostate cancer? 30 Aug 2009
• Effects of monovalent cations on Ca2+ uptake by skeletal and cardiac muscle sarcoplasmic reticulum. 21 Aug 2009
• Influence of trigger PSA and PSA kinetics on 11C-Choline PET/CT detection rate in patients with biochemical relapse after radical prostatectomy. 16 Aug 2009
• Choline in anxiety and depression: the Hordaland Health Study. 3 Aug 2009
• Effect of chorioamnionitis on brain development and injury in premature newborns. 30 Jul 2009
• Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis. 30 Jul 2009
• Measurement of glutathione in normal volunteers and stroke patients at 3T using J-difference spectroscopy with minimized subtraction errors. 30 Jul 2009
• Diffusion-weighted MR imaging: adjunct or alternative to T1-weighted MR imaging for prostate carcinoma bone metastases? 30 Jul 2009
• Cloning, expression, and characterization of a peculiar choline-binding beta-galactosidase from Streptococcus mitis. 22 Jul 2009
• Use of short echo time two-dimensional 1H-magnetic resonance spectroscopy in temporal lobe epilepsy with negative magnetic resonance imaging findings. 29 Jun 2009
• 1H HR-MAS and genomic analysis of human tumor biopsies discriminate between high and low grade astrocytomas. 29 Jun 2009
• Diabetic striatal disease: clinical presentation, neuroimaging, and pathology. 29 Jun 2009
• Impact of cerebrospinal fluid contamination on brain metabolites evaluation with 1H-MR spectroscopy: a single voxel study of the cerebellar vermis in patients with degenerative ataxias. 29 Jun 2009
• Nuclear magnetic resonance-based metabonomics reveals strong sex effect on plasma metabolism in 17-year-old Scandinavians and correlation to retrospective infant plasma parameters. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Choline'

Definition: A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

Chemical name: Ethanaminium, 2-hydroxy-N,N,N-trimethyl-

Registry Number: 62-49-7

Descriptor UI: D002794

Alternative terms: Choline; 2-Hydroxy-N,N,N-trimethylethanaminium; Choline O-Sulfate; Choline O Sulfate; O-Sulfate, Choline; Choline Chloride; Chloride, Choline; Choline Citrate; Citrate, Choline; Bursine; Vidine; Fagine; Choline Bitartrate; Bitartrate, Choline;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Lipotropic Agents; Nootropic Agents;

Tree Number: D02.033.100.291.211; D02.092.063.291.211; D02.092.877.883.333; D02.675.276.232;

Technical Notes: /biosyn /physiol permitted