Chromatin
Research News and Information

Sunday, November 22, 2009

Overexpression of Sp1 leads to p53-dependent apoptosis in cancer cells.

30 Oct 2009 Numerous studies have documented that Sp1 expression level were elevated in various human cancers. However, the promoters of many pro-apoptotic genes have been found to contain the Sp1 binding elements and are activated by Sp1 overexpression. To ... Read more...

Comprehensive mapping of long-range interactions reveals folding principles of the human genome.

7 Oct 2009 We describe Hi-C, a method that probes the three-dimensional architecture of whole genomes by coupling proximity-based ligation with massively parallel sequencing. We constructed spatial proximity maps of the human genome with Hi-C at a resolution ... Read more...

CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus.

6 Oct 2009 How cell type-specific differences in chromatin conformation are achieved and their contribution to gene expression are incompletely understood. Here we identify a cryptic upstream orchestrator of interferon-gamma (IFNG) transcription, which is ... Read more...

Latest indexed articles for 'Chromatin'

These are the very latest articles for this heading:

• Overexpression of Sp1 leads to p53-dependent apoptosis in cancer cells. 30 Oct 2009
• Comprehensive mapping of long-range interactions reveals folding principles of the human genome. 7 Oct 2009
• CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus. 6 Oct 2009
• Relative contributions of chromatin and kinetochores to mitotic spindle assembly. 3 Oct 2009
• Transcriptional control of the inflammatory response. 29 Sep 2009
• NURD keeps chromatin young. 29 Sep 2009
• Cooperative binding of two acetylation marks on a histone tail by a single bromodomain. 29 Sep 2009
• The Scc2/Scc4 cohesin loader determines the distribution of cohesin on budding yeast chromosomes. 29 Sep 2009
• Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions. 29 Sep 2009
• Stem cell pluripotency: a cellular trait that depends on transcription factors, chromatin state and a checkpoint deficient cell cycle. 29 Sep 2009
• The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks. 28 Sep 2009
• The human insulin gene is part of a large open chromatin domain specific for human islets. 26 Sep 2009
• JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin. 25 Sep 2009
• Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications. 23 Sep 2009
• Transcription dynamics. 22 Sep 2009
• The higher structure of chromatin in the LCR of the beta-globin locus changes during development. 21 Sep 2009
• Role of the polycomb protein EED in the propagation of repressive histone marks. 18 Sep 2009
• Recognition imaging of acetylated chromatin using a DNA aptamer. 14 Sep 2009
• TBP2 is essential for germ cell development by regulating transcription and chromatin condensation in the oocyte. 13 Sep 2009
• Entropic organization of interphase chromosomes. 12 Sep 2009

See a longer list of these articles.

Technical information about 'Chromatin'

Definition: The material of CHROMOSOMES. It is a complex of DNA; HISTONES; and nonhistone proteins (CHROMOSOMAL PROTEINS, NON-HISTONE) found within the nucleus of a cell.

Registry Number: 0

Descriptor UI: D002843

Alternative terms: Chromatin; Chromatins;

Allowable Qualifiers: classification; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology; genetics; isolation & purification;

Tree Number: A11.284.430.106.279.345.190.160.180; D12.776.664.224; G05.360.160.180;

History Note: 72