Chromatography, Liquid - Methods
Research News and Information

Sunday, November 22, 2009

gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment.

12 Oct 2009 Amyloid beta protein (Abeta), a pathogenic molecule associated with Alzheimer's disease, is produced by gamma-secretase, which cleaves the beta-carboxyl terminal fragment (betaCTF) of beta-amyloid precursor protein in the middle of its transmembrane ... Read more...

Simultaneous screening and quantification of 29 drugs of abuse in oral fluid by solid-phase extraction and ultraperformance LC-MS/MS.

29 Sep 2009 BACKGROUND: The European DRUID (Driving under the Influence of Drugs, Alcohol And Medicines) project calls for analysis of oral fluid (OF) samples, collected randomly and anonymously at the roadside from drivers in Denmark throughout 2008-2009. To ... Read more...

Validated LC coupled to ESI-MS/MS analysis for fentanyl in human plasma and UV analysis in applied reservoir transdermal patches using a simple and rapid procedure.

29 Sep 2009 BACKGROUND AND OBJECTIVES: Fentanyl has been used for cancer pain in transdermal formulation. The aim of the present study was to establish an analytical method for fentanyl in human plasma and in an applied transdermal reservoir patch ... Read more...

Latest indexed articles for 'Chromatography, Liquid - Methods'

These are the very latest articles for this heading:

• gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment. 12 Oct 2009
• Simultaneous screening and quantification of 29 drugs of abuse in oral fluid by solid-phase extraction and ultraperformance LC-MS/MS. 29 Sep 2009
• Validated LC coupled to ESI-MS/MS analysis for fentanyl in human plasma and UV analysis in applied reservoir transdermal patches using a simple and rapid procedure. 29 Sep 2009
• Comparative bioavailability of two formulations of sibutramine. 29 Sep 2009
• Structural characterization and identification of iridoid glycosides, saponins, phenolic acids and flavonoids in Flos Lonicerae Japonicae by a fast liquid chromatography method with diode-array detection and time-of-flight mass spectrometry. 29 Sep 2009
• Use of liquid chromatography/tandem mass spectrometry and online databases for identification of phosphocholines and lysophosphatidylcholines in human red blood cells. 29 Sep 2009
• Investigation of uremic analytes in hemodialysate and their structural elucidation from accurate mass maps generated by a multi-dimensional liquid chromatography/mass spectrometry approach. 29 Sep 2009
• Multi-residue analysis of eight thioamphetamine designer drugs in human urine by liquid chromatography/tandem mass spectrometry. 29 Sep 2009
• Comparison of urinary albumin quantification by immunoturbidimetry, competitive immunoassay, and protein-cleavage liquid chromatography-tandem mass spectrometry. 8 Sep 2009
• Clear differences in levels of a formaldehyde-DNA adduct in leukocytes of smokers and nonsmokers. 6 Sep 2009
• Isotope dilution method for determination of polybrominated diphenyl ethers using liquid chromatography coupled to negative ionization atmospheric pressure photoionization tandem mass spectrometry: validation and application to house dust. 30 Aug 2009
• Methodology for determining disulfide linkage patterns of closely spaced cysteine residues. 30 Aug 2009
• Accurate measurement of DNA methylation that is traceable to the international system of units. 30 Aug 2009
• Two-injection workflow for a liquid chromatography/LTQ-Orbitrap system to complete in vivo biotransformation characterization: demonstration with buspirone metabolite identification. 30 Aug 2009
• Mass spectrometric analysis of peptides from an immobilized lipase: focus on oxidative modifications. 30 Aug 2009
• Characterization of tanshinones with quinone reductase induction activity from Radix Salvia miltiorrhiza by liquid chromatography/tandem mass spectrometry. 30 Aug 2009
• Determination of 8-epi PGF(2alpha) concentrations as a biomarker of oxidative stress using triple-stage liquid chromatography/tandem mass spectrometry. 30 Aug 2009
• Fast analysis of isobaric grape anthocyanins by Chip-liquid chromatography/mass spectrometry. 30 Aug 2009
• Simultaneous analysis of (13)C-glutathione as its dimeric form GSSG and its precursor [1-(13)C]glycine using liquid chromatography/isotope ratio mass spectrometry. 30 Aug 2009
• An integrated serum proteomic approach capable of monitoring the low molecular weight proteome with sequencing of intermediate to large peptides. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Chromatography, Liquid'

Definition: Chromatographic techniques in which the mobile phase is a liquid.

Descriptor UI: D002853

Alternative terms: Chromatography, Liquid; Liquid Chromatography;

Allowable Qualifiers: classification; economics; history; instrumentation; methods; standards; trends; utilization; veterinary; statistics & numerical data; ethics;

Tree Number: E05.196.181.400;

History Note: 76

Technical Notes: an anal chem technique; NIM; DF: CHROMATOGR LIQUID