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Citalopram
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Definition of 'Citalopram'

A furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.

Common names: Citalopram; Cytalopram; Lu-10-171; Lu10171; Escitalopram; Lexapro

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Saturday, November 21, 2009

Depletion of selective serotonin reuptake inhibitors during sewage sludge composting.

30 Oct 2009 Sewage and sewage sludge is known to contain pharmaceuticals, and since sewage sludge is often used as fertilizer within agriculture, the reduction of the selective serotonin reuptake inhibitors (SSRIs) Citalopram, Sertraline, Paroxetine, ... Read more...


Effects of Lorazepam and citalopram on human defensive reactions: ethopharmacological differentiation of fear and anxiety.

5 Oct 2009 Drugs that are clinically effective against generalized anxiety disorder preferentially alter rodent risk assessment behavior, whereas drugs that are clinically effective against panic disorder preferentially alter rodent flight behavior. The ... Read more...


In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand.

29 Sep 2009 This study evaluated the in vitro and in vivo characteristics of a new dopamine transporter (DAT) radioligand, [(18)F]fluoroethyl(FE)PE2I, by autoradiography from postmortem human brain and by positron emission tomography (PET) in three cynomolgus ... Read more...

 

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Technical information about 'Citalopram'

Definition: A furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.

Chemical name: 5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-

Registry Number: 59729-33-8

Descriptor UI: D015283

Alternative terms: Citalopram; Cytalopram; Lu-10-171; Lu10171; Escitalopram; Lexapro;

Allowable Qualifiers: therapeutic use; toxicity; urine; chemistry; contraindications; agonists; administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution;

Pharmacological Action: Antidepressive Agents, Second-Generation; Serotonin Uptake Inhibitors;

Tree Number: D02.092.831.170; D02.626.320; D03.383.312.225.187; D03.438.127.187;

History Note: 1989; for ESCITALOPRAM use CITALOPRAM (NM) 2001-2002

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