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Coagulants - History
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Definition of 'Coagulants'

Exogenous substances used to promote blood coagulation. The endogenous BLOOD COAGULATION FACTORS are considered to be coagulants only when administered as drugs.

Common names: Coagulants

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Monday, November 23, 2009

Quantifying the source of infection for HIV-infected hemophiliacs in the U.K. from 1979 to 1984.

29 Apr 2009 There is considerable literature on the risk of HIV infection for individuals suffering from hemophilia A in the United Kingdom (U.K.) during the period 1979-1984 when the sources of Factor VIII clotting factor were contaminated with HIV. Toward the ... Read more...


Haemate P von Willebrand factor/factor VIII concentrate: 25 years of clinical experience.

30 Oct 2008 Although von Willebrand disease (VWD) has a very long history, our understanding and treatment of the bleeding disorder has only evolved during the past 50 years or so. It was not until the 1920s that VWD was first recognized as a disease separate ... Read more...


Control of coagulation: a gift of Canadian agriculture.

29 Nov 2006 Vitamin K, heparin and their antagonists remain the basis of coagulation therapies today, more than half a century after their discovery. Failure of blood clotting in chicks that were fed a fat-depleted diet was observed by William McFarlane, ... Read more...

 

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Technical information about 'Coagulants'

Definition: Exogenous substances used to promote blood coagulation. The endogenous BLOOD COAGULATION FACTORS are considered to be coagulants only when administered as drugs.

Registry Number: 0

Descriptor UI: D003029

Alternative terms: Coagulants;

Related Mesh Headings: Blood Coagulation Factors; Thrombin;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.954.502.270;

Online Note: search HEMOSTATICS 1966-74

History Note: 75; was see under HEMOSTATICS 1963-74

Technical Notes: consider also BLOOD COAGULATION /drug eff

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