Cocaine - Adverse effects
Research News and Information

Monday, November 23, 2009

Diffusion tensor imaging in cocaine dependence: regional effects of cocaine on corpus callosum and effect of cocaine administration route.

29 Sep 2009 Recent studies demonstrated that diffusion tensor imaging (DTI) can provide information regarding white matter integrity of the corpus callosum (CC). In this study, DTI parameters were compared between cocaine dependent subjects (CDs) and non-drug ... Read more...

[Cocaine-triggered ischaemic enteritis]

12 Sep 2009 A 25-year-old woman was hospitalized repeatedly during a 5-year period due to abdominal pain, change in stool pattern, high CRP and leucocytosis. Ultrasound and small bowel examination showed oedema of terminal ileum, and morbus Crohn was initially ... Read more...

Psychological mood state of opiate addicted women during pregnancy and postpartum in comparison to non-addicted healthy women.

30 Aug 2009 Opiate addiction has been widely documented to have negative impact on pregnancy course and outcome. Unfavorable psychosocial situation of addicted women predispose for poor processing of the physiological and psychological demands of pregnancy. ... Read more...

Latest indexed articles for 'Cocaine - Adverse effects'

These are the very latest articles for this heading:

• Diffusion tensor imaging in cocaine dependence: regional effects of cocaine on corpus callosum and effect of cocaine administration route. 29 Sep 2009
• [Cocaine-triggered ischaemic enteritis] 12 Sep 2009
• Psychological mood state of opiate addicted women during pregnancy and postpartum in comparison to non-addicted healthy women. 30 Aug 2009
• An unusual case of cocaine-induced maculopathy. 30 Aug 2009
• Drug-induced compulsive behaviors: exceptions to the rule. 30 Aug 2009
• Case 15-2009: a man with coma after cardiac arrest. 11 Aug 2009
• Understanding and promoting attachment. 30 Jul 2009
• Repeated dosing with oral cocaine in humans: assessment of direct effects, withdrawal, and pharmacokinetics. 30 Jul 2009
• Spectrum of electrocardiographic and angiographic coronary artery disease findings in patients with cocaine-associated myocardial infarction. 30 Jul 2009
• Plasticity of L-type Ca2+ channels after cocaine withdrawal. 30 Jul 2009
• An unrecognized presentation of cocaine-associated pneumomediastinum in the prehospital setting. 29 Jun 2009
• Reduced attentional scope in cocaine polydrug users. 23 Jun 2009
• Khantzian's 'self-medication hypothesis' of drug addiction and films by Martin Scorsese. 30 May 2009
• Pemphigus and drug addiction. 24 May 2009
• Protracted withdrawal from alcohol and drugs of abuse impairs long-term potentiation of intrinsic excitability in the juxtacapsular bed nucleus of the stria terminalis. 27 Apr 2009
• Cocaine withdrawal enhances long-term potentiation in rat hippocampus via changing the activity of corticotropin-releasing factor receptor subtype 2. 15 Apr 2009
• Functional MRI and response inhibition in children exposed to cocaine in utero. Preliminary findings. 15 Apr 2009
• Prenatal cocaine exposure and prolonged focus attention. Poor infant information processing ability or precocious maturation of attentional systems? 15 Apr 2009
• Executive functioning at ages 5 and 7 years in children with prenatal cocaine exposure. 15 Apr 2009
• Alteration of blood-brain barrier function by methamphetamine and cocaine. 5 Apr 2009

See a longer list of these articles.

Technical information about 'Cocaine'

Definition: An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.

Chemical name: 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-

Registry Number: 50-36-2

Descriptor UI: D003042

Alternative terms: Cocaine; Cocaine Hydrochloride; Hydrochloride, Cocaine; Cocaine HCl; HCl, Cocaine;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Vasoconstrictor Agents; Dopamine Uptake Inhibitors; Anesthetics, Local;

Tree Number: D02.145.074.722.388; D03.132.889.354; D03.605.869.388; D04.075.080.875.099.722.388;

Online Note: use COCAINE/analogs & derivatives to search COCAINE DERIVATIVES 1975-77; use TROPANES 1969-74

History Note: COCAINE DERIVATIVES was see under COCAINE 1975-77; was see under TROPANES 1969-74

Technical Notes: cocaine derivatives = COCAINE /analogs;CRACK COCAINE is available; cocaine addiction = COCAINE-RELATED DISORDERS