Cocaine-Related Disorders - Drug therapy
Research News and Information

Monday, November 23, 2009

Randomized, double-blind, placebo-controlled trial of vigabatrin for the treatment of cocaine dependence in Mexican parolees.

Aug 2009 OBJECTIVE: Cocaine dependence is associated with severe medical, psychiatric, and social morbidity, but no pharmacotherapy is approved for its treatment in the United States. The atypical antiepileptic vigabatrin (gamma-vinyl gamma-aminobutyric acid ... Read more...

mechanisms of disulfiram-induced cocaine abstinence: antabuse and cocaine relapse.

30 Jul 2009 The anti-alcoholism drug disulfiram (Antabuse), which is an inhibitor of aldehyde dehydrogenase, induces an aversive reaction to alcohol consumption and thereby helps patients reduce alcohol intake. Recent clinical trials, initiated to investigate ... Read more...

Buprenorphine medication versus voucher contingencies in promoting abstinence from opioids and cocaine.

30 Jul 2009 During a 12-week intervention, opioid dependent participants (N = 120) maintained on thrice-a-week (M, W, F) buprenorphine plus therapist and computer-based counseling were randomized to receive: (a) medication contingencies (MC = thrice weekly ... Read more...

Latest indexed articles for 'Cocaine-Related Disorders - Drug therapy'

These are the very latest articles for this heading:

• Expanding treatment options for cocaine dependence. 30 Oct 2009
• Randomized, double-blind, placebo-controlled trial of vigabatrin for the treatment of cocaine dependence in Mexican parolees. Aug 2009
• mechanisms of disulfiram-induced cocaine abstinence: antabuse and cocaine relapse. 30 Jul 2009
• Buprenorphine medication versus voucher contingencies in promoting abstinence from opioids and cocaine. 30 Jul 2009
• Modafinil for the treatment of cocaine dependence. 24 Jun 2009
• Multi-center trial of baclofen for abstinence initiation in severe cocaine-dependent individuals. 30 Apr 2009
• Psychological treatments for stimulant misuse, comparing and contrasting those for amphetamine dependence and those for cocaine dependence. 29 Apr 2009
• Valproate treatment and cocaine cue reactivity in cocaine dependent individuals. 14 Apr 2009
• Metabotropic glutamate receptor 5 (mGluR5) antagonists attenuate cocaine priming- and cue-induced reinstatement of cocaine seeking. 3 Apr 2009
• Neuropeptide S reinstates cocaine-seeking behavior and increases locomotor activity through corticotropin-releasing factor receptor 1 in mice. 30 Mar 2009
• Early abstinence in cocaine pharmacotherapy trials predicts successful treatment outcomes. 29 Mar 2009
• Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior. 9 Mar 2009
• The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats. 27 Feb 2009
• Molecular mechanisms of psychostimulant addiction. 27 Feb 2009
• The influence of intake urinalysis, psychopathology measures, and menstrual cycle phase on treatment compliance. 27 Feb 2009
• Overcoming cocaine or stimulant addiction. Medications offer modest help; vaccines are in development. 27 Feb 2009
• Effects of cocaine esterase following its repeated administration with cocaine in mice. 11 Feb 2009
• Cocaine 'body packers' and the clinical management of packet rupture. 30 Jan 2009
• Cocaine-induced myocardial infarction: not your average acute coronary syndrome. 30 Jan 2009
• Pronounced paranoia as a result of cocaine-disulfiram interaction: case report and mode of action. 30 Jan 2009

See a longer list of these articles.

Technical information about 'Cocaine-Related Disorders'

Definition: Disorders related or resulting from use of cocaine.

Descriptor UI: D019970

Alternative terms: Cocaine-Related Disorders; Cocaine Related Disorders; Cocaine-Related Disorder; Disorder, Cocaine-Related; Disorders, Cocaine-Related; Cocaine Abuse; Abuse, Cocaine; Cocaine Dependence; Dependence, Cocaine; Dependences, Cocaine; Cocaine Addiction; Addiction, Cocaine;

Allowable Qualifiers: blood; cerebrospinal fluid; classification; complications; diagnosis; diet therapy; drug therapy; economics; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; rehabilitation; surgery; therapy; urine; ultrasonography; virology;

Tree Number: C21.739.300; F03.900.300;

History Note: 98