Cocaine-Related Disorders - Radionuclide imaging
Research News and Information

Monday, November 23, 2009

Lower level of endogenous dopamine in patients with cocaine dependence: findings from PET imaging of D(2)/D(3) receptors following acute dopamine depletion.

30 Aug 2009 OBJECTIVE: Previous positron emission tomography (PET) imaging studies have demonstrated that cocaine dependence is associated with a decrease in dopamine type 2 and 3 (D(2)/D(3)) receptor binding in cocaine-dependent individuals relative to healthy ... Read more...

Cue-induced dopamine release predicts cocaine preference: positron emission tomography studies in freely moving rodents.

11 May 2009 Positron emission tomography studies in drug-addicted patients have shown that exposure to drug-related cues increases striatal dopamine, which displaces binding of the D(2) ligand, [(11)C]-raclopride. However, it is not known if animals will also ... Read more...

Dopamine D1 receptors in cocaine dependence measured with PET and the choice to self-administer cocaine.

26 Jan 2009 The goal of this study was to determine D(1) receptor availability in human cocaine-dependent (CD) subjects and matched healthy controls (HCs). In addition, the CD subjects performed cocaine self-administration sessions in order to explore the ... Read more...

Latest indexed articles for 'Cocaine-Related Disorders - Radionuclide imaging'

These are the very latest articles for this heading:

• Lower level of endogenous dopamine in patients with cocaine dependence: findings from PET imaging of D(2)/D(3) receptors following acute dopamine depletion. 30 Aug 2009
• Cue-induced dopamine release predicts cocaine preference: positron emission tomography studies in freely moving rodents. 11 May 2009
• Dopamine D1 receptors in cocaine dependence measured with PET and the choice to self-administer cocaine. 26 Jan 2009
• Dopamine transporter levels in cocaine dependent subjects. 18 Jun 2008
• Decreased brain dopamine transporters are related to cognitive deficits in HIV patients with or without cocaine abuse. 18 May 2008
• Dopamine increases in striatum do not elicit craving in cocaine abusers unless they are coupled with cocaine cues. 9 Oct 2007
• Amphetamine-induced dopamine release: markedly blunted in cocaine dependence and predictive of the choice to self-administer cocaine. 30 Mar 2007
• Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. 11 Sep 2006
• Sex differences in medial and lateral orbitofrontal cortex hypoperfusion in cocaine-dependent men and women. 30 Aug 2006
• PET imaging of dopamine D2 receptors in monkey models of cocaine abuse: genetic predisposition versus environmental modulation. 30 Jul 2005
• PET imaging in clinical drug abuse research. 30 Dec 2004
• Inhalation of crack cocaine can mimic pulmonary embolism. 30 Oct 2004
• Perfusion abnormalities and decision making in cocaine dependence. 29 Sep 2004
• Examining the effect of cerebral perfusion abnormality magnitude on cognitive performance in recently abstinent chronic cocaine abusers. 30 Mar 2004
• Drug dependence and addiction, III: Expectation and brain function in drug abuse. 30 Mar 2004
• Prefrontal cortical dysfunction in abstinent cocaine abusers. 30 Dec 2003
• Severity of neuropsychological impairment in cocaine and alcohol addiction: association with metabolism in the prefrontal cortex. 30 Dec 2003
• Resting regional cerebral blood flow and gambling task performance in cocaine-dependent subjects and healthy comparison subjects. 29 Sep 2003
• Regional cerebral blood flow in female cocaine-addicted subjects following limbic activation. 8 Sep 2003
• Aspirin or amiloride for cerebral perfusion defects in cocaine dependence. 18 Aug 2003

See a longer list of these articles.

Technical information about 'Cocaine-Related Disorders'

Definition: Disorders related or resulting from use of cocaine.

Descriptor UI: D019970

Alternative terms: Cocaine-Related Disorders; Cocaine Related Disorders; Cocaine-Related Disorder; Disorder, Cocaine-Related; Disorders, Cocaine-Related; Cocaine Abuse; Abuse, Cocaine; Cocaine Dependence; Dependence, Cocaine; Dependences, Cocaine; Cocaine Addiction; Addiction, Cocaine;

Allowable Qualifiers: blood; cerebrospinal fluid; classification; complications; diagnosis; diet therapy; drug therapy; economics; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; rehabilitation; surgery; therapy; urine; ultrasonography; virology;

Tree Number: C21.739.300; F03.900.300;

History Note: 98