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Collagen Type I - Genetics
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Definition of 'Collagen Type I'

The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and SKIN and consists of a heterotrimer of two alpha1(I) and one alpha2(I) chains.

Common names: Collagen Type I; Type 1 Collagen; Collagen, Type 1; Type I Collagen; Collagen, Type I; Procollagen Type I; Type I Procollagen; Procollagen, Type I; Pro alpha 1 Collagen; Pro alpha 2 Collagen; Collagen Type I, alpha1 Subunit; alpha1 Type 1 Collagen; Collagen Type I, alpha1 Chain; Collagen alpha1(I)

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Friday, March 12, 2010

Behavior of rat periodontal ligament cells on fibroblast growth factor-2-immobilized titanium surfaces treated by plasma modification.

29 Sep 2009 The aim of this study was to investigate the behavior of rat periodontal ligament (PDL) cells cultured on fibroblast growth factor-2 (FGF-2)-immobilized titanium surfaces treated by oxygen (O2) plasma. We used cell disks (15 mm in diameter), and ... Read more...


Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation.

18 Sep 2009 Eukaryotic cells have signalling pathways from the endoplasmic reticulum (ER) to cytosol and nuclei, to avoid excess accumulation of unfolded proteins in the ER. We previously identified a new type of ER stress transducer, OASIS, a bZIP (basic ... Read more...


Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism.

9 Sep 2009 The aim of the present study was to test the hypothesis that elevation of prorenin in plasma is sufficient to induce cardiac fibrosis. Normotensive cyp1a1ren-2 transgenic rats with normal plasma prorenin and aldosterone levels were given 0.125% ... Read more...

 

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Technical information about 'Collagen Type I'

Definition: The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and SKIN and consists of a heterotrimer of two alpha1(I) and one alpha2(I) chains.

Registry Number: 0

Descriptor UI: D024042

Alternative terms: Collagen Type I; Type 1 Collagen; Collagen, Type 1; Type I Collagen; Collagen, Type I; Procollagen Type I; Type I Procollagen; Procollagen, Type I; Pro alpha 1 Collagen; Pro alpha 2 Collagen; Collagen Type I, alpha1 Subunit; alpha1 Type 1 Collagen; Collagen Type I, alpha1 Chain; Collagen alpha1(I); Collagen Type I, alpha2 Subunit; Collagen alpha2(I); alpha2 Type 1 Collagen; Collagen Type I, alpha2 Chain; alpha-2 Type 1 Collagen;

Related Mesh Headings: Osteogenesis Imperfecta;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D05.750.078.280.300.100; D12.776.860.300.250.300.100;

History Note: 2002; use COLLAGEN 1966-2001; for ALPHA-2 TYPE 1 COLLAGEN use COLLAGEN 1987-2001; for PROCOLLAGEN TYPE I use PROCOLLAGEN 1986-2001; for TYPE I PROCOLLAGEN & PRO ALPHA 2 COLLAGEN use PROCOLLAGEN 1982-2001; for PRO ALPHA 1 COLLAGEN use PROCOLLAGEN 1988-2001

Technical Notes: precursors: coord IM with PROCOLLAGEN (IM)

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