Collagen Type I
Research News and Information

Saturday, November 21, 2009

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

29 Nov 2009 Osteosarcomas are the most prevalent primary bone tumors found in pediatric patients. To understand their molecular etiology, cell culture models are used to define disease mechanisms under controlled conditions. Many osteosarcoma cell lines (e.g., ... Read more...

OPLA scaffold, collagen I, and horse serum induce an higher degree of myogenic differentiation of adult rat cardiac stem cells.

29 Nov 2009 In the last few years, a major goal of cardiac research has been to drive stem cell differentiation to replace damaged myocardium. Several research groups have attempted to differentiate potential cardiac stem cells (CSCs) using bi- or ... Read more...

Natural history of markers of collagen turnover in patients with early diastolic dysfunction and impact of eplerenone.

25 Oct 2009 OBJECTIVES: This study was designed to evaluate the impact of eplerenone on collagen turnover in preserved systolic function heart failure (HFPSF). BACKGROUND: Despite growing interest in abnormal collagen metabolism as a feature of HFPSF with ... Read more...

Latest indexed articles for 'Collagen Type I'

These are the very latest articles for this heading:

• Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1). 29 Nov 2009
• OPLA scaffold, collagen I, and horse serum induce an higher degree of myogenic differentiation of adult rat cardiac stem cells. 29 Nov 2009
• Natural history of markers of collagen turnover in patients with early diastolic dysfunction and impact of eplerenone. 25 Oct 2009
• Tenascin-C and type I and III collagen expression in total Achilles tendon rupture. An immunohistochemical study. 29 Sep 2009
• Cocultures of osteoblasts and osteoclasts are influenced by local application of zoledronic acid incorporated in a poly(D,L-lactide) implant coating. 29 Sep 2009
• Behavior of rat periodontal ligament cells on fibroblast growth factor-2-immobilized titanium surfaces treated by plasma modification. 29 Sep 2009
• Mesenchymal stem cells and insulin-like growth factor-I gene-enhanced mesenchymal stem cells improve structural aspects of healing in equine flexor digitorum superficialis tendons. 29 Sep 2009
• Relation of high concentrations of plasma carboxy-terminal telopeptide of collagen type I with outcome in acute myocardial infarction. 29 Sep 2009
• High bone matrix turnover predicts blood levels of lead among perimenopausal women. 29 Sep 2009
• Attenuation of portal hypertension by natural taurine in rats with liver cirrhosis. 26 Sep 2009
• Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation. 18 Sep 2009
• Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition. 9 Sep 2009
• Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism. 9 Sep 2009
• Left ventricular function of isoproterenol-induced hypertrophied rat hearts perfused with blood: mechanical work and energetics. 2 Sep 2009
• Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts. 2 Sep 2009
• Rac1 promotes TGF-beta-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism. 31 Aug 2009
• The role of Tyr71 in Streptomyces trypsin on the recognition mechanism of structural protein substrates. 31 Aug 2009
• Toward regenerating a human thumb in situ. 30 Aug 2009
• Tensile stimulation of murine stem cell-collagen sponge constructs increases collagen type I gene expression and linear stiffness. 30 Aug 2009
• Composite chitosan/nano-hydroxyapatite scaffolds induce osteocalcin production by osteoblasts in vitro and support bone formation in vivo. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Collagen Type I'

Definition: The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and SKIN and consists of a heterotrimer of two alpha1(I) and one alpha2(I) chains.

Registry Number: 0

Descriptor UI: D024042

Alternative terms: Collagen Type I; Type 1 Collagen; Collagen, Type 1; Type I Collagen; Collagen, Type I; Procollagen Type I; Type I Procollagen; Procollagen, Type I; Pro alpha 1 Collagen; Pro alpha 2 Collagen; Collagen Type I, alpha1 Subunit; alpha1 Type 1 Collagen; Collagen Type I, alpha1 Chain; Collagen alpha1(I); Collagen Type I, alpha2 Subunit; Collagen alpha2(I); alpha2 Type 1 Collagen; Collagen Type I, alpha2 Chain; alpha-2 Type 1 Collagen;

Related Mesh Headings: Osteogenesis Imperfecta;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D05.750.078.280.300.100; D12.776.860.300.250.300.100;

History Note: 2002; use COLLAGEN 1966-2001; for ALPHA-2 TYPE 1 COLLAGEN use COLLAGEN 1987-2001; for PROCOLLAGEN TYPE I use PROCOLLAGEN 1986-2001; for TYPE I PROCOLLAGEN & PRO ALPHA 2 COLLAGEN use PROCOLLAGEN 1982-2001; for PRO ALPHA 1 COLLAGEN use PROCOLLAGEN 1988-2001

Technical Notes: precursors: coord IM with PROCOLLAGEN (IM)