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Collagen Type I
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Definition of 'Collagen Type I'

The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and SKIN and consists of a heterotrimer of two alpha1(I) and one alpha2(I) chains.

Common names: Collagen Type I; Type 1 Collagen; Collagen, Type 1; Type I Collagen; Collagen, Type I; Procollagen Type I; Type I Procollagen; Procollagen, Type I; Pro alpha 1 Collagen; Pro alpha 2 Collagen; Collagen Type I, alpha1 Subunit; alpha1 Type 1 Collagen; Collagen Type I, alpha1 Chain; Collagen alpha1(I)

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Sunday, November 08, 2009

Tenascin-C and type I and III collagen expression in total Achilles tendon rupture. An immunohistochemical study.

29 Sep 2009 Tendon tissue degeneration and changes in collagen composition play a role in spontaneous rupture of the human Achilles tendon. Tenascin-C has been shown to be present in the tissue pathology and changes in tissue loading. We made an ... Read more...


Cocultures of osteoblasts and osteoclasts are influenced by local application of zoledronic acid incorporated in a poly(D,L-lactide) implant coating.

29 Sep 2009 The antiresorptive activity of bisphosphonates such as zoledronic acid (ZOL) has been shown in vitro to be because of their effect on osteoclasts and osteoblasts. However, whether the effect of ZOL on monocultures might be reproducible on cocultures ... Read more...


Behavior of rat periodontal ligament cells on fibroblast growth factor-2-immobilized titanium surfaces treated by plasma modification.

29 Sep 2009 The aim of this study was to investigate the behavior of rat periodontal ligament (PDL) cells cultured on fibroblast growth factor-2 (FGF-2)-immobilized titanium surfaces treated by oxygen (O2) plasma. We used cell disks (15 mm in diameter), and ... Read more...

 

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Technical information about 'Collagen Type I'

Definition: The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and SKIN and consists of a heterotrimer of two alpha1(I) and one alpha2(I) chains.

Registry Number: 0

Descriptor UI: D024042

Alternative terms: Collagen Type I; Type 1 Collagen; Collagen, Type 1; Type I Collagen; Collagen, Type I; Procollagen Type I; Type I Procollagen; Procollagen, Type I; Pro alpha 1 Collagen; Pro alpha 2 Collagen; Collagen Type I, alpha1 Subunit; alpha1 Type 1 Collagen; Collagen Type I, alpha1 Chain; Collagen alpha1(I); Collagen Type I, alpha2 Subunit; Collagen alpha2(I); alpha2 Type 1 Collagen; Collagen Type I, alpha2 Chain; alpha-2 Type 1 Collagen;

Related Mesh Headings: Osteogenesis Imperfecta;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D05.750.078.280.300.100; D12.776.860.300.250.300.100;

History Note: 2002; use COLLAGEN 1966-2001; for ALPHA-2 TYPE 1 COLLAGEN use COLLAGEN 1987-2001; for PROCOLLAGEN TYPE I use PROCOLLAGEN 1986-2001; for TYPE I PROCOLLAGEN & PRO ALPHA 2 COLLAGEN use PROCOLLAGEN 1982-2001; for PRO ALPHA 1 COLLAGEN use PROCOLLAGEN 1988-2001

Technical Notes: precursors: coord IM with PROCOLLAGEN (IM)

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