Collagen Type V - Biosynthesis
Research News and Information

Sunday, November 22, 2009

Attenuation of alpha1 collagen production with antisense ribonucleic acid in cultured hypertrophic scar fibroblasts.

29 Apr 2009 BACKGROUND: It has been demonstrated that hypertrophic scar fibroblasts (HSFs) overexpress collagen messenger ribonucleic acid (mRNA) and protein, especially alpha1 collagen. Antisense nucleic acids are effective in inhibiting harmful or ... Read more...

Chronic low-dose isotretinoin treatment limits renal damage in subtotally nephrectomized rats.

14 Sep 2008 Retinoids are anti-proliferative and anti-inflammatory compounds. We had previously shown that retinoids alleviate kidney damage in acute models of renal disease. We now examined whether retinoids are also effective in a chronic renal ablation ... Read more...

Cutaneous metaplastic synovial cyst in Ehlers-Danlos syndrome: report of a second case.

30 Jan 2008 A cutaneous metaplastic synovial cyst is a rare entity that is probably caused by trauma or surgery. We report the second case of cutaneous metaplastic synovial cyst in a child with Ehlers-Danlos syndrome. His father is also affected with ... Read more...

Latest indexed articles for 'Collagen Type V - Biosynthesis'

These are the very latest articles for this heading:

• Attenuation of alpha1 collagen production with antisense ribonucleic acid in cultured hypertrophic scar fibroblasts. 29 Apr 2009
• Chronic low-dose isotretinoin treatment limits renal damage in subtotally nephrectomized rats. 14 Sep 2008
• Cutaneous metaplastic synovial cyst in Ehlers-Danlos syndrome: report of a second case. 30 Jan 2008
• Altered expression of matrix-related molecules in the development of chronic Thy1.1 nephritis. 3 Oct 2006
• Over-expression of hTERT in CHO K1 results in decreased apoptosis and reduced serum dependency. 4 Sep 2005
• Extracellular matrix synthesis, proliferation and death in mechanically stimulated human gingival fibroblasts in vitro. 18 Apr 2005
• Collagen, type V, alpha1 (COL5A1) is regulated by TGF-beta in osteoblasts. 30 Oct 2004
• Structurally different RGTAs modulate collagen-type expression by cultured aortic smooth muscle cells via different pathways involving fibroblast growth factor-2 or transforming growth factor-beta1. 5 May 2004
• Chronic venous insufficiency: dysregulation of collagen synthesis. 29 Jun 2003
• B-Myb repressor function is regulated by cyclin A phosphorylation and sequences within the C-terminal domain. Apr 2003
• Synovial remodeling process induced by type V collagen immunization in rabbits. 30 Dec 2002
• Antisense oligonucleotides reduce synthesis of procollagen alpha1 (V) chain in human patellar tendon fibroblasts: potential application in healing ligaments and tendons. 30 Dec 2002
• Biosynthetic processing of the pro-alpha 1(V)2pro-alpha 2(V) collagen heterotrimer by bone morphogenetic protein-1 and furin-like proprotein convertases. 10 Dec 2001

See a longer list of these articles.

Technical information about 'Collagen Type V'

Definition: A fibrillar collagen found widely distributed as a minor component in tissues that contain COLLAGEN TYPE I and COLLAGEN TYPE III. It is a heterotrimeric molecule composed of alpha1(V), alpha2(V) and alpha3(V) subunits. Several forms of collagen type V exist depending upon the composition of the subunits that form the trimer.

Registry Number: 0

Descriptor UI: D024062

Alternative terms: Collagen Type V; Type V Collagen; Collagen, Type V; Collagen Type V, alpha3 Subunit; Collagen Type V, alpha3 Chain; Collagen alpha3(V); Collagen Type V, alpha2 Subunit; Collagen Type V, alpha2 Chain; Collagen alpha2(V); Procollagen Type V; Type V Procollagen; Procollagen, Type V; V Procollagen, Type; Collagen Type V, alpha1 Subunit; Collagen Type V, alpha1 Chain; Collagen alpha1(V);

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D05.750.078.280.300.400; D12.776.860.300.250.300.400;

History Note: 2002; use COLLAGEN 1990-2001; for PROCOLLAGEN TYPE V use PROCOLLAGEN 1983-2001

Technical Notes: precursors: coord IM with PROCOLLAGEN (IM)