Collagen Type V
Research News and Information

Monday, November 23, 2009

Differential expression of collagen type V and XI alpha-1 in human ascending thoracic aortic aneurysms.

30 Jul 2009 BACKGROUND: The molecular mechanisms leading to ascending thoracic aortic aneurysms (ATAAs) remain unknown. We hypothesized that alterations in expression levels of specific fibrillar collagens occur during the aneurysmal process. METHODS: Surgical ... Read more...

Type V collagen-induced oral tolerance plus low-dose cyclosporine prevents rejection of MHC class I and II incompatible lung allografts.

29 Jun 2009 Autoimmunity to type V collagen (col(V)) is a major risk factor for lung allograft rejection. Although col(V)-induced oral tolerance abrogates rejection of minor histoincompatible lung transplants, its ability to prevent rejection of fully MHC ... Read more...

Molecular mechanisms of classical Ehlers-Danlos syndrome (EDS).

30 May 2009 Classical Ehlers-Danlos syndrome (EDS) is a heritable disorder characterized by joint hypermobility, skin hyperextensibility, and abnormal wound healing. The majority of affected individuals have alterations in 1 of the 2 type V collagen genes, ... Read more...

Latest indexed articles for 'Collagen Type V'

These are the very latest articles for this heading:

• Invited commentary. 30 Jul 2009
• Differential expression of collagen type V and XI alpha-1 in human ascending thoracic aortic aneurysms. 30 Jul 2009
• Type V collagen-induced oral tolerance plus low-dose cyclosporine prevents rejection of MHC class I and II incompatible lung allografts. 29 Jun 2009
• Molecular mechanisms of classical Ehlers-Danlos syndrome (EDS). 30 May 2009
• Attenuation of alpha1 collagen production with antisense ribonucleic acid in cultured hypertrophic scar fibroblasts. 29 Apr 2009
• Collagen type V modulates fibroblast behavior dependent on substrate stiffness. 4 Mar 2009
• Extracellular matrix remodelling in human diabetic neuropathy. 30 Jan 2009
• COL5A1 signal peptide mutations interfere with protein secretion and cause classic Ehlers-Danlos syndrome. 30 Jan 2009
• Differences in chain usage and cross-linking specificities of cartilage type V/XI collagen isoforms with age and tissue. 20 Dec 2008
• Absence of apparent disease causing mutations in COL5A3 in 13 patients with hypermobility Ehlers-Danlos syndrome. 13 Dec 2008
• Anti-type V collagen humoral immunity in lung transplant primary graft dysfunction. 13 Oct 2008
• Wound repair capability in EDS fibroblasts can be retrieved by exogenous type V collagen. Oct 2008
• The role of type V collagen fibril as an ECM that induces the motility of glomerular endothelial cells. 23 Sep 2008
• Chronic low-dose isotretinoin treatment limits renal damage in subtotally nephrectomized rats. 14 Sep 2008
• Intercellular accumulation of type V collagen fibrils in accordance with cell aggregation. 4 Sep 2008
• [Expression and distribution of type I, III and V collagens in skin lesions from patients with systemic sclerosis] 30 Aug 2008
• Demosponge and sea anemone fibrillar collagen diversity reveals the early emergence of A/C clades and the maintenance of the modular structure of type V/XI collagens from sponge to human. 9 Aug 2008
• Effects of a bioscaffold on collagen fibrillogenesis in healing medial collateral ligament in rabbits. 30 Jul 2008
• A glycine-valine substitution in alpha2 type V procollagen associated with recurrent cervical artery dissection. 25 Jun 2008
• MMP-12 catalytic domain recognizes triple helical peptide models of collagen V with exosites and high activity. 4 Jun 2008

See a longer list of these articles.

Technical information about 'Collagen Type V'

Definition: A fibrillar collagen found widely distributed as a minor component in tissues that contain COLLAGEN TYPE I and COLLAGEN TYPE III. It is a heterotrimeric molecule composed of alpha1(V), alpha2(V) and alpha3(V) subunits. Several forms of collagen type V exist depending upon the composition of the subunits that form the trimer.

Registry Number: 0

Descriptor UI: D024062

Alternative terms: Collagen Type V; Type V Collagen; Collagen, Type V; Collagen Type V, alpha3 Subunit; Collagen Type V, alpha3 Chain; Collagen alpha3(V); Collagen Type V, alpha2 Subunit; Collagen Type V, alpha2 Chain; Collagen alpha2(V); Procollagen Type V; Type V Procollagen; Procollagen, Type V; V Procollagen, Type; Collagen Type V, alpha1 Subunit; Collagen Type V, alpha1 Chain; Collagen alpha1(V);

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D05.750.078.280.300.400; D12.776.860.300.250.300.400;

History Note: 2002; use COLLAGEN 1990-2001; for PROCOLLAGEN TYPE V use PROCOLLAGEN 1983-2001

Technical Notes: precursors: coord IM with PROCOLLAGEN (IM)