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Computational Biology
Research News and Information
Definition of 'Computational Biology'A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories applicable to MOLECULAR BIOLOGY and areas of computer-based techniques for solving biological problems including manipulation of models and datasets. |
Saturday, November 21, 2009
29 Nov 2009 
Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...
Nov 2009 We previously characterized a LOV protein PpSB2-LOV, present in the common soil bacterium Pseudomonas putida, that exhibits a plant phototropin LOV-like photochemistry [Krauss, U., Losi, A., Gartner, W., Jaeger, K. E., and Eggert, T. (2005) Phys. ... Read more...
From consensus structure prediction to RNA gene finding.
30 Oct 2009 Reliable structure prediction is a prerequisite for most types of bioinformatical analysis of RNA. Since the accuracy of structure prediction from single sequences is limited, one often resorts to computing the consensus structure for a set of ... Read more...
Latest indexed articles for 'Computational Biology'
These are the very latest articles for this heading:
- Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
- Computational cognitive neuroscience.
22 Nov 2009 - Mutual exchange of kinetic properties by extended mutagenesis in two short LOV domain proteins from Pseudomonas putida. Nov 2009
- From consensus structure prediction to RNA gene finding. 30 Oct 2009
- The use of covariance models to annotate RNAs in whole genomes. 30 Oct 2009
- Annotating non-coding transcription using functional genomics strategies. 30 Oct 2009
- Predicting structurally conserved contacts for homologous proteins using sequence conservation filters. 30 Oct 2009
- Application of the fuzzy-oil-drop model to membrane protein simulation. 30 Oct 2009
- Quantitative analysis and prediction of curvature in leucine-rich repeat proteins. 30 Oct 2009
- Combining interface core and whole interface descriptors in postscan processing of protein-protein docking models. 30 Oct 2009
- Native state dynamics and mechanical properties of human topoisomerase I within a structure-based coarse-grained model. 30 Oct 2009
- A distance-dependent atomic knowledge-based potential and force for discrimination of native structures from decoys. 30 Oct 2009
- Template-free protein structure prediction and quality assessment with an all-atom free-energy model. 30 Oct 2009
- Computational methods for discovering structural variation with next-generation sequencing. 30 Oct 2009
- A non-human primate BAC resource to study interchromosomal segmental duplications. 25 Oct 2009
- Are algal genes in nonphotosynthetic protists evidence of historical plastid endosymbioses? 18 Oct 2009
- Anopheles gambiae alkaline phosphatase is a functional receptor of Bacillus thuringiensis jegathesan Cry11Ba toxin. 18 Oct 2009
- Highlights from the 5th International Society for Computational Biology Student Council Symposium at the 17th Annual International Conference on Intelligent Systems for Molecular Biology and the 8th European Conference on Computational Biology. 17 Oct 2009
- Regulation of phenylacetic acid degradation genes of Burkholderia cenocepacia K56-2. 16 Oct 2009
- Modalities, modes, and models in functional neuroimaging. 14 Oct 2009
See a longer list of these articles.
Technical information about 'Computational Biology'
Definition: A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories applicable to MOLECULAR BIOLOGY and areas of computer-based techniques for solving biological problems including manipulation of models and datasets.
Descriptor UI: D019295
Alternative terms: Computational Biology; Biology, Computational; Bio-Informatics; Bioinformatics; Computational Molecular Biology; Molecular Biology, Computational;
Related Mesh Headings: Medical Informatics;
Allowable Qualifiers: classification; economics; education; history; instrumentation; legislation & jurisprudence; manpower; methods; organization & administration; standards; trends; statistics & numerical data; ethics;
Tree Number: H01.158.273.180;
History Note: 97
Technical Notes: SPEC; SPEC qualif; coord IM with specific biol spec (IM); DF: COMPUTATIONAL BIOL