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Controlled Clinical Trials as Topic
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Definition of 'Controlled Clinical Trials as Topic'

Clinical trials involving one or more test treatments, at least one control treatment, specified outcome measures for evaluating the studied intervention, and a bias-free method for assigning patients to the test treatment. The treatment may be drugs, devices, or procedures studied for diagnostic, therapeutic, or prophylactic effectiveness. Control measures include placebos, active medicines, no-treatment, dosage forms and regimens, historical comparisons, etc. When randomization using mathematical techniques, such as the use of a random numbers table, is employed to assign patients to test or control treatments, the trials are characterized as RANDOMIZED CONTROLLED TRIALS AS TOPIC.

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Monday, November 23, 2009

Angiotensin receptor blockers: role in hypertension management, cardiovascular risk reduction, and nephropathy.

29 Sep 2009 BACKGROUND: The renin-angiotensin system (RAS) plays a central pathogenic role in the development of hypertension and associated vascular disorders. However, whether the two main classes of agents that blunt RAS activity-angiotensin-converting ... Read more...


Quality circles to improve prescribing of primary care physicians. Three comparative studies.

30 Aug 2009 PURPOSE: To determine the effectiveness of quality circles on prescribing patterns of primary care physicians in Germany and to explore the influence of specific factors on changes. METHODS: Three large non-randomised comparative studies were ... Read more...


Treatment options for children and adolescents with bipolar disorder.

30 Aug 2009 Bipolar disorder is an increasingly common diagnosis in children and adolescents. Although psychosocial interventions are important for these young patients, treatment guidelines presently focus on pharmacologic therapy in the acute treatment of ... Read more...

 

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Technical information about 'Controlled Clinical Trials as Topic'

Definition: Clinical trials involving one or more test treatments, at least one control treatment, specified outcome measures for evaluating the studied intervention, and a bias-free method for assigning patients to the test treatment. The treatment may be drugs, devices, or procedures studied for diagnostic, therapeutic, or prophylactic effectiveness. Control measures include placebos, active medicines, no-treatment, dosage forms and regimens, historical comparisons, etc. When randomization using mathematical techniques, such as the use of a random numbers table, is employed to assign patients to test or control treatments, the trials are characterized as RANDOMIZED CONTROLLED TRIALS AS TOPIC.

Descriptor UI: D018849

Alternative terms: Controlled Clinical Trials as Topic; Clinical Trials, Controlled as Topic;

Related Mesh Headings: Control Groups;

Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics; legislation & jurisprudence;

Tree Number: E05.318.760.535.365; E05.337.250.365; N05.715.360.775.235.387; N06.850.520.450.535.365;

History Note: 2008(1995); use CLINICAAL TRIALS 1980-1984

Technical Notes: for general design, methodology, economics, etc. of clinical trials; a different heading CONTROLLED CLINICAL TRIAL is used for reports of a specific clinical trial

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