Coronary Disease - Genetics
Research News and Information

Tuesday, November 24, 2009

Insertion/deletion polymorphism in alpha2-adrenergic receptor gene is a genetic risk factor for sudden cardiac death.

29 Sep 2009 BACKGROUND: Adrenoceptors mediate contraction of vascular smooth muscle and induce coronary vasoconstriction in humans. A deletion variant of the human alpha(2B)-adrenoreseptor of glutamic acid residues has been associated with impaired receptor ... Read more...

Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity.

19 Sep 2009 BACKGROUND: Shortening of mean telomere length (TL) in white blood cells is correlated with the development of coronary heart disease (CHD) and with increased mortality due to infectious disease. The goal of the present study was to investigate ... Read more...

APOE genotype, lipids, and coronary heart disease risk: a prospective population study.

8 Aug 2009 BACKGROUND: The risk of coronary heart disease (CHD) may be related to genetic mutations in the production of apolipoprotein E via alterations to the metabolism of CHD-related blood lipids such as low-density lipoprotein cholesterol and ... Read more...

Latest indexed articles for 'Coronary Disease - Genetics'

These are the very latest articles for this heading:

• Insertion/deletion polymorphism in alpha2-adrenergic receptor gene is a genetic risk factor for sudden cardiac death. 29 Sep 2009
• Cardiovascular event risk: high-density lipoprotein and paraoxonase. 27 Sep 2009
• Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity. 19 Sep 2009
• Risk factors: Lipoprotein(a) and coronary disease-moving closer to causality. 30 Aug 2009
• Genomewide association studies of stroke. 11 Aug 2009
• APOE genotype, lipids, and coronary heart disease risk: a prospective population study. 8 Aug 2009
• Routine referral. 6 Aug 2009
• Coronary heart disease risk, aspirin use, and apolipoprotein(a) 4399Met allele in the Atherosclerosis Risk in Communities (ARIC) study. 29 Jun 2009
• Influence of genetic polymorphisms in oxidative stress related genes and smoking on plasma MDA-LDL, soluble CD40 ligand, E-selectin and soluble ICAM1 levels in patients with coronary artery disease. 29 Jun 2009
• The tenacity of the coronary candidate: how people with familial hypercholesterolaemia construct raised cholesterol and coronary heart disease. 29 Jun 2009
• Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. 29 Jun 2009
• Value of genetic profiling for the prediction of coronary heart disease. 29 Jun 2009
• Apolipoprotein E, CI and B gene polymorphisms in a sample of patients with coronary heart disease in the Kuwaiti population. 31 May 2009
• Antihypertensive pharmacogenetic effect of fibrinogen-beta variant -455G>A on cardiovascular disease, end-stage renal disease, and mortality: the GenHAT study. 30 May 2009
• Familial risk for common diseases in primary care: the Family Healthware Impact Trial. 30 May 2009
• Genetic variation in Fc gamma receptor IIa and risk of coronary heart disease: negative results from two large independent populations. 27 May 2009
• Paraoxonase 1 polymorphisms and risk of myocardial infarction in women and men. 13 May 2009
• APOC3 mutation, serum triglyceride concentrations, and coronary heart disease. 12 May 2009
• Haplotype analysis of the stromelysin-1 (MMP3) and gelatinase B (MMP9) genes in relation to coronary heart disease. 9 May 2009
• Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease. 7 May 2009

See a longer list of these articles.

Technical information about 'Coronary Disease'

Definition: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Descriptor UI: D003327

Alternative terms: Coronary Disease; Coronary Diseases; Disease, Coronary; Diseases, Coronary; Coronary Heart Disease; Coronary Heart Diseases; Disease, Coronary Heart; Diseases, Coronary Heart; Heart Disease, Coronary; Heart Diseases, Coronary;

Related Mesh Headings: Coronary Artery Bypass; Myocardial Revascularization; Angioplasty, Transluminal, Percutaneous Coronary;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C14.280.647.250; C14.907.585.250;

Technical Notes: general or unspecified; prefer specifics