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Corticosterone - Metabolism
Research News and Information
Definition of 'Corticosterone'An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437) Common names: Corticosterone |
Monday, November 23, 2009
12 Oct 2009 
Systemic injection of lipopolysaccharide (LPS) is a widely used model of immune/inflammatory challenge, which can invoke a host of CNS responses, including activation of the hypothalamic-pituitary-adrenal (HPA) axis. Inducible vascular prostaglandin ... Read more...
Corticosterone reduces dendritic complexity in developing hippocampal CA1 neurons.
30 Aug 2009 Although prolonged stress and corticosteroid exposure induce morphological changes in the hippocampal CA3 area, the adult CA1 area is quite resistant to such changes. Here we addressed the question whether elevated corticosteroid hormone levels ... Read more...
27 Aug 2009 Di-(2-ethylhexyl) phthalate (DEHP) and its metabolite mono-(2-ethylhexyl) phthalate (MEHP) have been classified as toxicants to the reproductive system at the testis level and DEHP may also impair reproductive axis function at the pituitary levels. ... Read more...
Latest indexed articles for 'Corticosterone - Metabolism'
These are the very latest articles for this heading:
- Cerebrovascular cyclooxygenase-1 expression, regulation, and role in hypothalamic-pituitary-adrenal axis activation by inflammatory stimuli. 12 Oct 2009
- Corticosterone reduces dendritic complexity in developing hippocampal CA1 neurons. 30 Aug 2009
- Mono-(2-ethylhexyl) phthalate (MEHP) regulates glucocorticoid metabolism through 11beta-hydroxysteroid dehydrogenase 2 in murine gonadotrope cells. 27 Aug 2009
- Effects of dehydroepiandrosterone sulfate on the conversion of corticosterone into 11-dehydrocorticosterone in stress: a regulatory scheme. 19 Jul 2009
- Stress and corticosterone enhance cognitive recovery from hippocampal stroke in rats. 12 Jul 2009
- Effects of aggressive encounters on plasma corticosteroid-binding globulin and its ligands in white-crowned sparrows. 6 Jul 2009
- Glucocorticoid status affects antidepressant regulation of locus coeruleus tyrosine hydroxylase and dorsal raphé tryptophan hydroxylase gene expression. Jul 2009
- Invasive and noninvasive measurement of stress in laying hens kept in conventional cages and in floor pens. 29 Jun 2009
- "Green odor" inhalation by rats down-regulates stress-induced increases in Fos expression in stress-related forebrain regions. 25 Jun 2009
- Development of stress response in nestling pied flycatchers. 7 Jun 2009
- Scavenger Receptor BI Protects against Septic Death through Its Role in Modulating Inflammatory Response. 31 May 2009
- Corticosteroids disrupt amphibian metamorphosis by complex modes of action including increased prolactin expression. 25 May 2009
- Behavior in the forced swim test and neurochemical changes in the hippocampus in young rats after 2-week zinc deprivation. 18 May 2009
- Central opioid inhibition of neuroendocrine stress responses in pregnancy in the rat is induced by the neurosteroid allopregnanolone. 18 May 2009
- Five amino acids in the innermost cavity of the substrate binding cleft of organic cation transporter 1 interact with extracellular and intracellular corticosterone. 10 May 2009
- Expression of prepro-ghrelin and related receptor genes in the rat adrenal gland and evidences that ghrelin exerts a potent stimulating effect on corticosterone secretion by cultured rat adrenocortical cells. 2 May 2009
- Steroid production and excretion by the pregnant mouse, particularly in relation to pregnancies with fetuses deficient in Delta7-sterol reductase (Dhcr7), the enzyme associated with Smith-Lemli-Opitz syndrome. May 2009
- Chronically elevated corticosterone in the dorsolateral bed nuclei of stria terminalis increases anxiety-like behavior. May 2009
- Sublethal effects of methylmercury on fecal metabolites of testosterone, estradiol, and corticosterone in captive juvenile white ibises (Eudocimus albus). 29 Apr 2009
- Tracking stress: localisation, deposition and stability of corticosterone in feathers. 29 Apr 2009
See a longer list of these articles.
Technical information about 'Corticosterone'
Definition: An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
Chemical name: Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, (11beta)-
Registry Number: 50-22-6
Descriptor UI: D003345
Alternative terms: Corticosterone;
Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Pharmacological Action: Anti-Inflammatory Agents;
Tree Number: D04.808.745.745.654.237; D06.472.040.585.353.237;
Technical Notes: /biosyn /physiol permitted