Coumarins - Chemistry
Research News and Information

Sunday, November 22, 2009

Responsive polymer nanoparticles formed by poly(ether amine) containing coumarin units and a poly(ethylene oxide) short chain.

30 Aug 2009 We reported a novel poly(ether amine) (PEAC) containing poly(ethylene oxide) (PEO) short blocks and coumarin units, which was synthesized by nucleophilic addition/ring-opening polymerization of diepoxy and diamine monomers. PEAC can be directly ... Read more...

Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida.

30 Aug 2009 Two new sesquiterpene coumarins, designated 5'-acetoxy-8'-hydroxyumbelliprenin (1) and 10'R-acetoxy-11'-hydroxyumbelliprenin (2), and a new diterpene, 15-hydroxy-6-en-dehydroabietic acid (3), along with 27 known compounds, were isolated from a ... Read more...

Cytotoxic constituents of Soymida febrifuga from Myanmar.

30 Aug 2009 The 70% ethanol extract of Soymida febrifuga was found to kill PANC-1 human pancreatic cancer cells preferentially under nutrition-deprived conditions at a concentration of 10 microg/mL. Phytochemical investigation led to the isolation of 27 ... Read more...

Latest indexed articles for 'Coumarins - Chemistry'

These are the very latest articles for this heading:

• Responsive polymer nanoparticles formed by poly(ether amine) containing coumarin units and a poly(ethylene oxide) short chain. 30 Aug 2009
• Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida. 30 Aug 2009
• Cytotoxic constituents of Soymida febrifuga from Myanmar. 30 Aug 2009
• Minor furanocoumarins and coumarins in grapefruit peel oil as inhibitors of human cytochrome P450 3A4. 30 Aug 2009
• Chirality transfer effects in proline-substituted coumarin compounds. 11 Aug 2009
• Energetics of coumarin and chromone. 11 Aug 2009
• High-throughput fluorescence assay of cytochrome P450 3A4. 4 Aug 2009
• Coumarins from Angelica lucida L.--antibacterial activities. 25 Jul 2009
• Total synthesis of (+)-angelmarin. 15 Jul 2009
• Tyrosinase inhibitor activity of coumarin-resveratrol hybrids. 11 Jul 2009
• Design and synthesis of some thiazolidin-4-ones based on (7-hydroxy-2-oxo-2H-chromen-4-yl) acetic acid. 8 Jul 2009
• Synthesis and evaluation of novel substituted 5-hydroxycoumarin and pyranocoumarin derivatives exhibiting significant antiproliferative activity against breast cancer cell lines. Jul 2009
• An application of high-speed counter-current chromatography coupled with electrospray ionization mass spectrometry for separation and online identification of coumarins from Peucedanum praeruptorum Dunn. 30 Jun 2009
• Anion sensor-based ratiometric peptide probe for protein kinase activity. 30 Jun 2009
• Coumestan glycosides from the stem bark of Cylicodiscus gabunensis. 29 Jun 2009
• Fluorescent probe for detection of fluoride in water and bioimaging in A549 human lung carcinoma cells. 27 Jun 2009
• Dissimilar in vitro and in vivo effects of ellagic acid and its microbiota-derived metabolites, urolithins, on the cytochrome P450 1A1. 22 Jun 2009
• Fluorescence dynamics of coumarin C522 on reduced-charge montmorillonite in aqueous dispersion. 14 Jun 2009
• A chemotaxonomic study of nine Canarian Sideritis species. 13 Jun 2009
• Copper(II) complexes of coumarin-derived Schiff bases and their anti-Candida activity. 9 Jun 2009

See a longer list of these articles.

Technical information about 'Coumarins'

Definition: Synthetic or naturally occurring substances related to coumarin, the delta-lactone of coumarinic acid. The various coumarins have a wide range of proposed actions and uses including as ANTICOAGULANTS, pharmaceutical aids, indicators and reagents, photoreactive substances, and ANTINEOPLASTIC AGENTS.

Registry Number: 0

Descriptor UI: D003374

Alternative terms: Coumarins; Benzopyran-2-ones; Benzopyran 2 ones; Coumarines; 1,2-Benzo-Pyrones; 1,2 Benzo Pyrones; 1,2-Benzopyrones; 1,2 Benzopyrones;

Related Mesh Headings: Anticoagulants; Indicators and Reagents; Pharmaceutic Aids; Pyrones;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anticoagulants; Antineoplastic Agents; Indicators and Reagents;

Tree Number: D03.438.150.446; D03.830.219.446;