Coumarins
Research News and Information

Sunday, November 22, 2009

Laser treatment of benign prostatic hyperplasia in patients on oral anticoagulant therapy: a review.

20 Dec 2009 We assessed the therapeutic efficacy and safety of laser prostatectomy (LP) for treating benign prostatic hyperplasia (BPH) in patients on oral anticoagulation. We systematically reviewed previous reports, using the Pubmed database and ... Read more...

Responsive polymer nanoparticles formed by poly(ether amine) containing coumarin units and a poly(ethylene oxide) short chain.

30 Aug 2009 We reported a novel poly(ether amine) (PEAC) containing poly(ethylene oxide) (PEO) short blocks and coumarin units, which was synthesized by nucleophilic addition/ring-opening polymerization of diepoxy and diamine monomers. PEAC can be directly ... Read more...

Conceptual DFT properties-based 3D QSAR: analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.

30 Aug 2009 Structure-activity relationships of 46 P450 2A6 inhibitors were analyzed using the 3D-QSAR methodology. The analysis was carried out to confront the use of traditional steric and electrostatic fields with that of a number of fields reflecting ... Read more...

Latest indexed articles for 'Coumarins'

These are the very latest articles for this heading:

• Laser treatment of benign prostatic hyperplasia in patients on oral anticoagulant therapy: a review. 20 Dec 2009
• Responsive polymer nanoparticles formed by poly(ether amine) containing coumarin units and a poly(ethylene oxide) short chain. 30 Aug 2009
• Conceptual DFT properties-based 3D QSAR: analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme. 30 Aug 2009
• Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida. 30 Aug 2009
• Cytotoxic constituents of Soymida febrifuga from Myanmar. 30 Aug 2009
• Minor furanocoumarins and coumarins in grapefruit peel oil as inhibitors of human cytochrome P450 3A4. 30 Aug 2009
• Ligand binding analyses of the putative peptide transporter YjdL from E. coli display a significant selectivity towards dipeptides. 20 Aug 2009
• N(alpha)-tosyl-L-phenylalanine chloromethyl ketone induces caspase-dependent apoptosis in transformed human B cell lines with transcriptional down-regulation of anti-apoptotic HS1-associated protein X-1. 11 Aug 2009
• Chirality transfer effects in proline-substituted coumarin compounds. 11 Aug 2009
• Energetics of coumarin and chromone. 11 Aug 2009
• Osthole, a potential antidiabetic agent, alleviates hyperglycemia in db/db mice. 10 Aug 2009
• High-throughput fluorescence assay of cytochrome P450 3A4. 4 Aug 2009
• Efficacy of coumarin on hepatic key enzymes of glucose metabolism in chemical induced type 2 diabetic rats. 4 Aug 2009
• Anti-inflammatory activity and possible mechanism of extract from Mikania laevigata in carrageenan-induced peritonitis. 30 Jul 2009
• Induction of quinone reductase activity by psoralidin isolated from Psoralea corylifolia in mouse hepa 1c1c7 cells. 29 Jul 2009
• Coumarins from Angelica lucida L.--antibacterial activities. 25 Jul 2009
• Total synthesis of (+)-angelmarin. 15 Jul 2009
• Capillary electrophoresis for screening of 20S proteasome inhibitors. 14 Jul 2009
• Tyrosinase inhibitor activity of coumarin-resveratrol hybrids. 11 Jul 2009
• Design and synthesis of some thiazolidin-4-ones based on (7-hydroxy-2-oxo-2H-chromen-4-yl) acetic acid. 8 Jul 2009

See a longer list of these articles.

Technical information about 'Coumarins'

Definition: Synthetic or naturally occurring substances related to coumarin, the delta-lactone of coumarinic acid. The various coumarins have a wide range of proposed actions and uses including as ANTICOAGULANTS, pharmaceutical aids, indicators and reagents, photoreactive substances, and ANTINEOPLASTIC AGENTS.

Registry Number: 0

Descriptor UI: D003374

Alternative terms: Coumarins; Benzopyran-2-ones; Benzopyran 2 ones; Coumarines; 1,2-Benzo-Pyrones; 1,2 Benzo Pyrones; 1,2-Benzopyrones; 1,2 Benzopyrones;

Related Mesh Headings: Anticoagulants; Indicators and Reagents; Pharmaceutic Aids; Pyrones;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anticoagulants; Antineoplastic Agents; Indicators and Reagents;

Tree Number: D03.438.150.446; D03.830.219.446;