Craniosynostoses - Embryology
Research News and Information

Sunday, November 22, 2009

EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis.

27 Feb 2009 Heterozygous loss of Twist1 function causes coronal synostosis in both mice and humans. We showed previously that in mice this phenotype is associated with a defect in the neural crest-mesoderm boundary within the coronal suture, as well as with a ... Read more...

Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology.

27 Jan 2009 Activating mutations of FGFRs1-3 cause craniosynostosis (CS), the premature fusion of cranial bones, in man and mouse. The mechanisms by which such mutations lead to CS have been variously ascribed to increased osteoblast proliferation, ... Read more...

Cranial sutures: a brief review.

30 Mar 2008 Craniosynostosis, or the premature fusion of one or more cranial sutures, is a relatively common congenital defect that causes a number of morphologic and functional abnormalities. With advances in genetics and molecular biology, research of ... Read more...

Latest indexed articles for 'Craniosynostoses - Embryology'

These are the very latest articles for this heading:

• EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis. 27 Feb 2009
• Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology. 27 Jan 2009
• Cranial sutures: a brief review. 30 Mar 2008
• Cellular dynamics and tissue interactions of the dura mater during head development. 29 Nov 2007
• [Craniosynostosis in the embryo.] 27 Feb 2007
• Growth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studies. 30 Oct 2005
• Three-dimensional sonographic description of the fetal frontal bones and metopic suture. 30 Oct 2005
• Intrauterine fetal constraint induces chondrocyte apoptosis and premature ossification of the cranial base. 29 Sep 2005
• Prenatal diagnosis of cranial vault defects. 29 Jun 2005
• Immunolocalization of androgen receptor in the developing craniofacial skeleton. 30 Oct 2004
• Molecular mechanisms in calvarial bone and suture development, and their relation to craniosynostosis. 30 Mar 2003
• Craniosynostosis and altered patterns of fetal TGF-beta expression induced by intrauterine constraint. 30 May 2002
• Transforming growth factor-beta3 (Tgf-beta3) down-regulates Tgf-beta3 receptor type I (Tbetar-I) during rescue of cranial sutures from osseous obliteration. 30 Jan 2002
• FGF-4 or FGF-2 administration induces apoptosis, collagen type I expression, and mineralization in the developing coronal suture. 29 Jun 2001
• Toward an understanding of nonsyndromic craniosynostosis: altered patterns of TGF-beta receptor and FGF receptor expression induced by intrauterine head constraint. 29 Apr 2001
• New developments in cranial suture research. 30 Jan 2001
• [Cranial and facial anomalies] 30 Dec 2000
• Craniosynostosis syndromes: from genes to premature fusion of skull bones. 29 Sep 1999
• Positional changes of the frontoparietal ossification centers in perinatal craniosynostotic rabbits. 30 Mar 1999
• Tracing craniosynostosis to its developmental stage through bone center displacement. 30 Mar 1999

See a longer list of these articles.

Technical information about 'Craniosynostoses'

Definition: Premature closure of one or more sutures of the skull.

Descriptor UI: D003398

Alternative terms: Craniosynostoses; Craniosynostosis; Acrocephaly; Oxycephaly;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; ultrastructure; urine; veterinary; ultrasonography; virology;

Tree Number: C05.116.099.370.894.232; C05.660.207.240; C05.660.906.364; C16.131.621.207.240; C16.131.621.906.364;

Online Note: use CRANIOSYNOSTOSES to search OXYCEPHALY 1966-78

History Note: OXYCEPHALY was see under CRANIOSYNOSTOSES 1963-78

Technical Notes: do not use /congen & do not coord with INFANT, NEWBORN, DISEASES