Creatine Kinase
Research News and Information

Monday, November 23, 2009

The SLCO1B1*5 genetic variant is associated with statin-induced side effects.

18 Oct 2009 OBJECTIVES: We sought to identify single nucleotide polymorphisms associated with mild statin-induced side effects. BACKGROUND: Statin-induced side effects can interfere with therapy. Single nucleotide polymorphisms in cytochrome P450 enzymes impair ... Read more...

Exercise above the ischemic threshold and serum markers of myocardial injury.

29 Sep 2009 BACKGROUND: Current guidelines for exercise training in coronary patients state that in the presence of exercise-induced ischemia, the heart rate during exercise should be at least 10 beats/min below the heart rate associated with an ST segment ... Read more...

Malignant hyperthermia, coexisting disorders, and enzymopathies: risks and management options.

29 Sep 2009 Clinical episodes and abnormal laboratory tests compatible with a diagnosis of malignant hyperthermia have been observed in patients with a diversity of syndromes, enzymopathies, and coexisting disorders thereby raising the likelihood of causal ... Read more...

Latest indexed articles for 'Creatine Kinase'

These are the very latest articles for this heading:

• The SLCO1B1*5 genetic variant is associated with statin-induced side effects. 18 Oct 2009
• Exercise above the ischemic threshold and serum markers of myocardial injury. 29 Sep 2009
• Malignant hyperthermia, coexisting disorders, and enzymopathies: risks and management options. 29 Sep 2009
• Prognostic impact of Q waves on presentation and ST resolution in patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention. 13 Sep 2009
• Searching for the needle in the Haystacks. 3 Sep 2009
• Changes in the mechanical properties of human quadriceps muscle after eccentric exercise. 30 Aug 2009
• [Randomized controlled trials on the influence and mechanism of manipulation on delayed onset muscle soreness after eccentric exercise] 30 Aug 2009
• A cytoskeletal tropomyosin can compromise the structural integrity of skeletal muscle. 30 Aug 2009
• Insulin inhibits myocardial ischemia-induced apoptosis and alleviates chronic adverse changes in post-ischemic cardiac structure and function. 30 Aug 2009
• Post-polio syndrome: epidemiologic and prognostic aspects in Brazil. 30 Aug 2009
• Acclimation to heat during incubation: 4. Blood hormones and metabolites in broilers exposed to daily high temperatures. 30 Aug 2009
• Urine dipstick testing to rule out rhabdomyolysis in patients with suspected heat injury. 30 Aug 2009
• Restless legs syndrome with periodic limb movements: a possible cause of idiopathic hyperCKemia. 23 Aug 2009
• Kaempferol protects against rat striatal degeneration induced by 3-nitropropionic acid. 11 Aug 2009
• [Application of monitoring phosphocreatine kinase continuously and dynamically in early diagnosis of compartment syndrome] 30 Jul 2009
• Incidence, risk factors, and severity of herpesvirus infections in a cohort of 121 patients with primary dermatomyositis and dermatomyositis associated with a malignant neoplasm. 30 Jul 2009
• Recovery time in a case of gemfibrozil and simvastatin-associated rhabdomyolysis. 30 Jul 2009
• Genetic variation in RYR1 and malignant hyperthermia phenotypes. 29 Jul 2009
• Protective effects of caspase-9 and poly(ADP-ribose) polymerase inhibitors on ischemia-reperfusion-induced myocardial injury. 29 Jul 2009
• Deep brain stimulation in chorea acanthocytosis. 28 Jul 2009

See a longer list of these articles.

Technical information about 'Creatine Kinase'

Definition: A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.

Chemical name: ATP:creatine N-phosphotransferase

Registry Number: EC 2.7.3.2

Descriptor UI: D003402

Alternative terms: Creatine Kinase; Kinase, Creatine; ATP Creatine Phosphotransferase; Creatine Phosphotransferase, ATP; Phosphotransferase, ATP Creatine; Creatine Phosphokinase; Phosphokinase, Creatine; ADP Phosphocreatine Phosphotransferase; Phosphocreatine Phosphotransferase, ADP; Phosphotransferase, ADP Phosphocreatine; Macro-Creatine Kinase; Macro Creatine Kinase;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.913.696.640.150;