Creatinine - Analogs & derivatives
Research News and Information

Monday, November 23, 2009

Controlled synthesis of polylactides using biogenic creatinine carboxylate initiators.

9 May 2009 Two biogenetic guanidine carboxylates, i.e., creatinine acetate (CRA) and creatinine glycolate (CRG) based on creatinine (CR) were synthesized and structurally characterized by (1)H NMR, (13)C NMR and X-ray diffraction (XRD) analysis of the single ... Read more...

Response disengagement on a spatial self-ordered sequencing task: effects of regionally selective excitotoxic lesions and serotonin depletion within the prefrontal cortex.

4 May 2009 Prefrontal cortex (PFC) is critical for self-ordered response sequencing. Patients with frontal lobe damage are impaired on response sequencing tasks, and increased blood flow has been reported in ventrolateral and dorsolateral PFC in subjects ... Read more...

Production of uremic toxin methylguanidine from creatinine via creatol on activated carbon.

18 Feb 2009 The mixture of creatinine, activated charcoal and water was stirred. As a result the conversion of creatinine into two products was observed. (1)H, (13)C NMR and HMBC spectra were recorded and the chemical shifts assigned. Two uremic toxins: creatol ... Read more...

Latest indexed articles for 'Creatinine - Analogs & derivatives'

These are the very latest articles for this heading:

• Controlled synthesis of polylactides using biogenic creatinine carboxylate initiators. 9 May 2009
• Response disengagement on a spatial self-ordered sequencing task: effects of regionally selective excitotoxic lesions and serotonin depletion within the prefrontal cortex. 4 May 2009
• Production of uremic toxin methylguanidine from creatinine via creatol on activated carbon. 18 Feb 2009
• Creatine kinase-mediated ATP supply fuels actin-based events in phagocytosis. 9 Mar 2008
• Urinary excretion of creatol, an in vivo biomarker of hydroxyl radical, in patients with chronic renal failure. 30 Dec 2006
• Creatol, an oxidative product of creatinine in kidney transplant patients, as a useful determinant of renal function: a preliminary study. 30 Aug 2006
• 1H and 13C NMR spectra and solution structures of novel derivatives of 5-substituted creatinines. 19 Aug 2006
• Comparison of hydroxyl radical generation in patients undergoing coronary artery bypass grafting with and without cardiopulmonary bypass. 30 Jan 2006
• Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats. 29 Nov 2004
• Isoleucine 69 and valine 325 form a specificity pocket in human muscle creatine kinase. 31 Oct 2004
• Evaluation of oxidative stress markers for the early diagnosis of allograft rejection in feline renal allotransplant recipients with normal renal function. 29 Sep 2004
• Elimination of serotonergic cells induces a marked increase in generation of dopaminergic neurons from mesencephalic precursors. 29 Sep 2003
• Global 5-HT depletion attenuates the ability of amphetamine to decrease impulsive choice on a delay-discounting task in rats. 31 Aug 2003
• Inhibition of the mitochondrial permeability transition by creatine kinase substrates. Requirement for microcompartmentation. 3 Mar 2003
• Inhibition by heparin of protein kinase C activation and hydroxyl radical generation in puromycin aminonucleoside treated isolated rat hepatocytes. 30 Jan 2003
• Hodgkin disease-derived cell lines expressing ubiquitous mitochondrial creatine kinase show growth inhibition by cyclocreatine treatment independent of apoptosis. 30 Oct 2001
• Mutagenesis of two acidic active site residues in human muscle creatine kinase: implications for the catalytic mechanism. 11 Mar 2001
• The role of protein kinase C in the increased generation in isolated rat hepatocytes of the hydroxyl radical by puromycin aminonucleoside. 30 May 2000
• Effects of cyclocreatine in rat hepatocarcinogenesis model. 29 Apr 2000
• Creatol, an oxidative product of creatinine in hemodialysis patients. 30 Dec 1999

See a longer list of these articles.

Technical information about 'Creatinine'

Chemical name: 4H-Imidazol-4-one, 2-amino-1,5-dihydro-1-methyl-

Registry Number: 60-27-5

Descriptor UI: D003404

Alternative terms: Creatinine; Krebiozen; Creatinine Sulfate Salt; Salt, Creatinine Sulfate; Sulfate Salt, Creatinine;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D03.383.129.308.207;

Online Note: search CREATINE AND CREATININE under CREATINE 1966-67

History Note: 68; CREATINE AND CREATININE was heading 1963-67

Technical Notes: do not confuse with CREATINE