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Cross-Linking Reagents - Metabolism
Research News and Information
Definition of 'Cross-Linking Reagents'Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other. Common names: Cross-Linking Reagents; Reagents, Cross-Linking; Crosslinking Reagents; Reagents, Crosslinking; Bifunctional Reagents; Reagents, Bifunctional; Cross Linking Reagents; Linking Reagents, Cross; Reagents, Cross Linking |
Monday, November 23, 2009
Splice site strength-dependent activity and genetic buffering by poly-G runs.
11 Sep 2009 
Pre-mRNA splicing is regulated through the combinatorial activity of RNA motifs, including splice sites and splicing regulatory elements. Here we show that the activity of the G-run (polyguanine sequence) class of splicing enhancer elements is ... Read more...
Antitumor IgE adjuvanticity: key role of Fc epsilon RI.
9 Sep 2009 Working with C57BL/6 mouse tumor models, we had previously demonstrated that vaccination with IgE-coated tumor cells can protect against tumor challenge, an observation that supports the involvement of IgE in antitumor immunity. The adjuvant effect ... Read more...
29 Aug 2009 Tn5 transposase cleaves the transposon end using a hairpin intermediate on the transposon end. This involves a flipped base that is stacked against a tryptophan residue in the protein. However, many other members of the cut-and-paste transposase ... Read more...
Latest indexed articles for 'Cross-Linking Reagents - Metabolism'
These are the very latest articles for this heading:
- Pillars article: antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 1987. 165: 302-319.
29 Sep 2009 - Splice site strength-dependent activity and genetic buffering by poly-G runs. 11 Sep 2009
- Antitumor IgE adjuvanticity: key role of Fc epsilon RI. 9 Sep 2009
- Base flipping in V(D)J recombination: insights into the mechanism of hairpin formation, the 12/23 rule, and the coordination of double-strand breaks. 29 Aug 2009
- Stimulatory and inhibitory killer Ig-like receptor molecules are expressed and functional on lupus T cells. 10 Aug 2009
- Identification of the major TG4 cross-linking sites in the androgen-dependent SVS I exclusively expressed in mouse seminal vesicle. 30 Jul 2009
- Membrane-bound Fas ligand requires RIP1 for efficient activation of caspase-8 within the death-inducing signaling complex. 27 Jul 2009
- Genetic analysis of repair and damage tolerance mechanisms for DNA-protein cross-links in Escherichia coli. 15 Jul 2009
- Myocardial lysyl oxidase regulation of cardiac remodeling in a murine model of diet-induced metabolic syndrome. 8 Jul 2009
- Effect of cross-link structure on DNA interstrand cross-link repair synthesis. 29 Jun 2009
- Sphingosine kinase 1 is pivotal for Fc epsilon RI-mediated mast cell signaling and functional responses in vitro and in vivo. 29 Jun 2009
- Structural insights into the calmodulin-Munc13 interaction obtained by cross-linking and mass spectrometry. 28 Jun 2009
- Cellular membrane disruption by amyloid fibrils involved intermolecular disulfide cross-linking. 28 Jun 2009
- Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration. 24 Jun 2009
- Enhanced expression of haemoglobin scavenger receptor in accumulated macrophages of culprit lesions in acute coronary syndromes. 23 Jun 2009
- Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. 15 Jun 2009
- Transient oscillatory force-length behavior of activated airway smooth muscle. 10 Jun 2009
- The cataract-associated R14C mutant of human gamma D-crystallin shows a variety of intermolecular disulfide cross-links: a Raman spectroscopic study. 7 Jun 2009
- Photoaffinity labeling reveals nuclear proteins that uniquely recognize cisplatin-DNA interstrand cross-links. 7 Jun 2009
- Specific interaction between tomato HsfA1 and HsfA2 creates hetero-oligomeric superactivator complexes for synergistic activation of heat stress gene expression. 30 May 2009
See a longer list of these articles.
Technical information about 'Cross-Linking Reagents'
Definition: Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
Registry Number: 0
Descriptor UI: D003432
Alternative terms: Cross-Linking Reagents; Reagents, Cross-Linking; Crosslinking Reagents; Reagents, Crosslinking; Bifunctional Reagents; Reagents, Bifunctional; Cross Linking Reagents; Linking Reagents, Cross; Reagents, Cross Linking;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; chemical synthesis; classification; diagnostic use; economics; history; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; chemistry; contraindications;
Tree Number: D27.720.470.410.210;
History Note: 80
Technical Notes: D25-26 qualif