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Cross-Linking Reagents
Research News and Information
Definition of 'Cross-Linking Reagents'Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other. Common names: Cross-Linking Reagents; Reagents, Cross-Linking; Crosslinking Reagents; Reagents, Crosslinking; Bifunctional Reagents; Reagents, Bifunctional; Cross Linking Reagents; Linking Reagents, Cross; Reagents, Cross Linking |
Monday, November 23, 2009
Enhanced biological stability of collagen with incorporation of PAMAM dendrimer.
29 Sep 2009 
The crosslinking methods of collagen using glutaraldehyde (GTA) and 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC)/N-hydroxysuccinimide (NHS) are frequently performed in biomedical applications, but both methods still have their own ... Read more...
29 Sep 2009 We have been investigating thermoresponsive hydrogel nanoparticle composite networks to develop photopolymerized hydrogels to deliver drugs for prevention of restenosis after angioplasty. These composite systems can form a gel under physiological ... Read more...
Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death.
25 Sep 2009 Germ cells are sensitive to genotoxins, and ovarian failure and infertility are major side effects of chemotherapy in young patients with cancer. Here we describe the c-Abl-TAp63 pathway activated by chemotherapeutic DNA-damaging drugs in model ... Read more...
Latest indexed articles for 'Cross-Linking Reagents'
These are the very latest articles for this heading:
- Pillars article: antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 1987. 165: 302-319.
29 Sep 2009 - Enhanced biological stability of collagen with incorporation of PAMAM dendrimer. 29 Sep 2009
- Cytocompatibility studies of an in situ photopolymerized thermoresponsive hydrogel nanoparticle system using human aortic smooth muscle cells. 29 Sep 2009
- Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death. 25 Sep 2009
- Residues gating the periplasmic pathway of LacY. 21 Sep 2009
- A novel synthetic route for the preparation of hydrolytically degradable synthetic hydrogels. 13 Sep 2009
- Splice site strength-dependent activity and genetic buffering by poly-G runs. 11 Sep 2009
- Antitumor IgE adjuvanticity: key role of Fc epsilon RI. 9 Sep 2009
- Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication. 9 Sep 2009
- Topo IIIalpha and BLM act within the Fanconi anemia pathway in response to DNA-crosslinking agents. 2 Sep 2009
- A versatile catalyst system for Suzuki-Miyaura cross-coupling reactions of C(sp(2))-tosylates and mesylates. Sep 2009
- Nonprotein based enrichment method to analyze peptide cross-linking in protein complexes. 30 Aug 2009
- Effects of PEG hydrogel crosslinking density on protein diffusion and encapsulated islet survival and function. 30 Aug 2009
- Gelatin nanofibrous membrane fabricated by electrospinning of aqueous gelatin solution for guided tissue regeneration. 30 Aug 2009
- Mechanical properties of tannic-acid-treated dentin matrix. 30 Aug 2009
- Heterobifunctional isotope-labeled amine-reactive photo-cross-linker for structural investigation of proteins by matrix-assisted laser desorption/ionization tandem time-of-flight and electrospray ionization LTQ-Orbitrap mass spectrometry. 30 Aug 2009
- Base flipping in V(D)J recombination: insights into the mechanism of hairpin formation, the 12/23 rule, and the coordination of double-strand breaks. 29 Aug 2009
- Substrate binding site flexibility of the small heat shock protein molecular chaperones. 24 Aug 2009
- Allosteric beta-propeller signalling in TolB and its manipulation by translocating colicins. 18 Aug 2009
- Stimuli-responsive coacervate induced in binary functionalized poly(N-isopropylacrylamide) aqueous system and novel method for preparing semi-ipn microgel using the coacervate. 16 Aug 2009
See a longer list of these articles.
Technical information about 'Cross-Linking Reagents'
Definition: Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
Registry Number: 0
Descriptor UI: D003432
Alternative terms: Cross-Linking Reagents; Reagents, Cross-Linking; Crosslinking Reagents; Reagents, Crosslinking; Bifunctional Reagents; Reagents, Bifunctional; Cross Linking Reagents; Linking Reagents, Cross; Reagents, Cross Linking;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; chemical synthesis; classification; diagnostic use; economics; history; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; chemistry; contraindications;
Tree Number: D27.720.470.410.210;
History Note: 80
Technical Notes: D25-26 qualif