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Cross-Over Studies
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Definition of 'Cross-Over Studies'

Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)

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Saturday, November 21, 2009

Triggering of nocturnal arrhythmias by sleep-disordered breathing events.

Nov 2009 OBJECTIVES: This study sought to evaluate respiratory disturbances as potential triggers for arrhythmia in patients with sleep-disordered breathing (SDB). BACKGROUND: SDB is associated with an increased risk of atrial fibrillation and nonsustained ... Read more...


Optimising the unprotected airway with a prototype Jaw-Thrust-Device--a prospective randomised cross-over study.

30 Oct 2009 Despite being a standard procedure during induction of anaesthesia, facemask ventilation can be a major challenge especially for inexperienced anaesthetists. We manufactured a Jaw-Thrust-Device designed to keep the patient's jaws in an optimised ... Read more...


A prospective, randomised, cross-over trial comparing the EndoFlex and standard tracheal tubes in patients with predicted easy intubation.

30 Oct 2009 We aimed to determine if using the EndoFlex tracheal tube on the first intubation attempt provided improved placement times and intubation success compared with a standard-type tracheal tube in 50 patients undergoing gynaecological surgery in a ... Read more...

 

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Technical information about 'Cross-Over Studies'

Definition: Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)

Descriptor UI: D018592

Alternative terms: Cross-Over Studies; Cross Over Studies; Cross-Over Study; Studies, Cross-Over; Study, Cross-Over; Crossover Studies; Crossover Study; Studies, Crossover; Study, Crossover; Cross-Over Trials; Cross Over Trials; Trial, Cross-Over; Trials, Cross-Over; Crossover Trials; Trial, Crossover; Trials, Crossover; Cross-Over Design; Cross Over Design; Cross-Over Designs; Design, Cross-Over; Designs, Cross-Over; Crossover Design; Crossover Designs; Design, Crossover; Designs, Crossover;

Tree Number: E05.318.780.150; N05.715.360.780.150; N06.850.520.445.150;

History Note: 95

Technical Notes: usually drug or other ther study; IM GEN only; coord NIM with specific ther (IM); coord NIM also with any other study design such as RANDOM ALLOCATION; DOUBLE-BLIND METHOD; etc. (NIM); when pertinent add CLINICAL TRIAL (PT) or RANDOMIZED CONTROLLED TRIAL (PT); no qualif

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