Cyclic AMP Response Element-Binding Protein - Metabolism
Research News and Information

Sunday, November 22, 2009

Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine- and cAMP-induced CREB-dependent gene transcription.

5 Oct 2009 cAMP can stimulate the transcription of many activity-dependent genes via activation of the transcription factor, cAMP response element-binding protein (CREB). However, in mouse cortical neuron cultures, prior to synaptogenesis, neither cAMP nor ... Read more...

Isoflurane inhibits cyclic adenosine monophosphate response element-binding protein phosphorylation and calmodulin translocation to the nucleus of SH-SY5Y cells.

29 Sep 2009 BACKGROUND: Calmodulin (CaM) activation by Ca(2+), its translocation to the nucleus, and stimulation of phosphorylation of cyclic adenosine monophosphate response element-binding protein (CREB) (P-CREB) are necessary for new gene expression and have ... Read more...

Characterization of small RNAs in aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB.

22 Sep 2009 Memory storage and memory-related synaptic plasticity rely on precise spatiotemporal regulation of gene expression. To explore the role of small regulatory RNAs in learning-related synaptic plasticity, we carried out massive parallel sequencing to ... Read more...

Latest indexed articles for 'Cyclic AMP Response Element-Binding Protein - Metabolism'

These are the very latest articles for this heading:

• Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine- and cAMP-induced CREB-dependent gene transcription. 5 Oct 2009
• Isoflurane inhibits cyclic adenosine monophosphate response element-binding protein phosphorylation and calmodulin translocation to the nucleus of SH-SY5Y cells. 29 Sep 2009
• Characterization of small RNAs in aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB. 22 Sep 2009
• IGF-I maintains calpastatin expression and attenuates apoptosis in several models of photoreceptor cell death. 30 Aug 2009
• The hypoxia-inducible factor 1/NOR-1 axis regulates the survival response of endothelial cells to hypoxia. 29 Aug 2009
• Hydrostatic pressure-dependent changes in cyclic AMP signaling in optic nerve head astrocytes from Caucasian and African American donors. 18 Aug 2009
• 4'-Demethylnobiletin, a bioactive metabolite of nobiletin enhancing PKA/ERK/CREB signaling, rescues learning impairment associated with NMDA receptor antagonism via stimulation of the ERK cascade. 16 Aug 2009
• Cell cycle regulatory effects of retinoic Acid and forskolin are mediated by the cyclin C gene. 12 Aug 2009
• ER stress controls iron metabolism through induction of hepcidin. 12 Aug 2009
• Endothelin-1 regulates oligodendrocyte development. 10 Aug 2009
• Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle. 5 Aug 2009
• Apolipoprotein E4 domain interaction induces endoplasmic reticulum stress and impairs astrocyte function. 5 Aug 2009
• Simvastatin acutely reduces ischemic brain damage in the immature rat via Akt and CREB activation. 3 Aug 2009
• Skeletal muscle deiodinase type 2 regulation during illness in mice. 3 Aug 2009
• DFP initiated early alterations of PKA/p-CREB pathway and differential persistence of beta-tubulin subtypes in the CNS of hens contributes to OPIDN. 3 Aug 2009
• 5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice. 3 Aug 2009
• c-Fos expression in preoptic nuclei as a marker of sleep rebound in the rat. Aug 2009
• Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner. Aug 2009
• Cannabinoid receptor type 1 protects against age-related osteoporosis by regulating osteoblast and adipocyte differentiation in marrow stromal cells. 30 Jul 2009
• Lotus (Nelumbo nuficera) flower essential oil increased melanogenesis in normal human melanocytes. 29 Jul 2009

See a longer list of these articles.

Technical information about 'Cyclic AMP Response Element-Binding Protein'

Definition: A protein that has been shown to function as a calcium-regulated transcription factor as well as a substrate for depolarization-activated CALCIUM-CALMODULIN DEPENDENT PROTEIN KINASES. This protein functions to integrate both calcium and cAMP signals.

Registry Number: 0

Descriptor UI: D017362

Alternative terms: Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Responsive DNA-Binding Protein; Cyclic AMP Responsive DNA Binding Protein; CREB Protein; DNA-Binding Protein, Cyclic AMP-Responsive; DNA Binding Protein, Cyclic AMP Responsive; cAMP Response Element-Binding Protein; cAMP Response Element Binding Protein;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260.108.184; D12.776.930.127.184;

Online Note: use DNA-BINDING PROTEIN, CYCLIC AMP-RESPONSIVE (NM) to search CYCLIC AMP-RESPONSIVE DNA-BINDING PROTEIN 1989-92

History Note: 93; was CYCLIC AMP-RESPONSIVE DNA-BINDING PROTEIN (NM) 1989-92