Cyclic AMP Response Element-Binding Protein
Research News and Information

Sunday, November 22, 2009

Molecular and cellular approaches to memory allocation in neural circuits.

14 Oct 2009 Although memory allocation is a subject of active research in computer science, little is known about how the brain allocates information within neural circuits. There is an extensive literature on how specific types of memory engage different parts ... Read more...

Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine- and cAMP-induced CREB-dependent gene transcription.

5 Oct 2009 cAMP can stimulate the transcription of many activity-dependent genes via activation of the transcription factor, cAMP response element-binding protein (CREB). However, in mouse cortical neuron cultures, prior to synaptogenesis, neither cAMP nor ... Read more...

Isoflurane inhibits cyclic adenosine monophosphate response element-binding protein phosphorylation and calmodulin translocation to the nucleus of SH-SY5Y cells.

29 Sep 2009 BACKGROUND: Calmodulin (CaM) activation by Ca(2+), its translocation to the nucleus, and stimulation of phosphorylation of cyclic adenosine monophosphate response element-binding protein (CREB) (P-CREB) are necessary for new gene expression and have ... Read more...

Latest indexed articles for 'Cyclic AMP Response Element-Binding Protein'

These are the very latest articles for this heading:

• Molecular and cellular approaches to memory allocation in neural circuits. 14 Oct 2009
• Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine- and cAMP-induced CREB-dependent gene transcription. 5 Oct 2009
• Isoflurane inhibits cyclic adenosine monophosphate response element-binding protein phosphorylation and calmodulin translocation to the nucleus of SH-SY5Y cells. 29 Sep 2009
• A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair. 22 Sep 2009
• Characterization of small RNAs in aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB. 22 Sep 2009
• Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation. 18 Sep 2009
• IGF-I maintains calpastatin expression and attenuates apoptosis in several models of photoreceptor cell death. 30 Aug 2009
• Hop bitter acids efficiently block inflammation independent of GRalpha, PPARalpha, or PPARgamma. 30 Aug 2009
• The hypoxia-inducible factor 1/NOR-1 axis regulates the survival response of endothelial cells to hypoxia. 29 Aug 2009
• Hydrostatic pressure-dependent changes in cyclic AMP signaling in optic nerve head astrocytes from Caucasian and African American donors. 18 Aug 2009
• 4'-Demethylnobiletin, a bioactive metabolite of nobiletin enhancing PKA/ERK/CREB signaling, rescues learning impairment associated with NMDA receptor antagonism via stimulation of the ERK cascade. 16 Aug 2009
• Cell cycle regulatory effects of retinoic Acid and forskolin are mediated by the cyclin C gene. 12 Aug 2009
• ER stress controls iron metabolism through induction of hepcidin. 12 Aug 2009
• Endothelin-1 regulates oligodendrocyte development. 10 Aug 2009
• Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle. 5 Aug 2009
• Apolipoprotein E4 domain interaction induces endoplasmic reticulum stress and impairs astrocyte function. 5 Aug 2009
• Simvastatin acutely reduces ischemic brain damage in the immature rat via Akt and CREB activation. 3 Aug 2009
• Skeletal muscle deiodinase type 2 regulation during illness in mice. 3 Aug 2009
• DFP initiated early alterations of PKA/p-CREB pathway and differential persistence of beta-tubulin subtypes in the CNS of hens contributes to OPIDN. 3 Aug 2009
• 5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice. 3 Aug 2009

See a longer list of these articles.

Technical information about 'Cyclic AMP Response Element-Binding Protein'

Definition: A protein that has been shown to function as a calcium-regulated transcription factor as well as a substrate for depolarization-activated CALCIUM-CALMODULIN DEPENDENT PROTEIN KINASES. This protein functions to integrate both calcium and cAMP signals.

Registry Number: 0

Descriptor UI: D017362

Alternative terms: Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Responsive DNA-Binding Protein; Cyclic AMP Responsive DNA Binding Protein; CREB Protein; DNA-Binding Protein, Cyclic AMP-Responsive; DNA Binding Protein, Cyclic AMP Responsive; cAMP Response Element-Binding Protein; cAMP Response Element Binding Protein;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260.108.184; D12.776.930.127.184;

Online Note: use DNA-BINDING PROTEIN, CYCLIC AMP-RESPONSIVE (NM) to search CYCLIC AMP-RESPONSIVE DNA-BINDING PROTEIN 1989-92

History Note: 93; was CYCLIC AMP-RESPONSIVE DNA-BINDING PROTEIN (NM) 1989-92