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Cytokines - Immunology
Research News and Information
Definition of 'Cytokines'Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner. Common names: Cytokines |
Monday, November 23, 2009
30 Oct 2009 
Patients with metastatic renal cell carcinoma (mRCC) have a limited life expectancy but still a subset of these patients develop immune and clinical responses after immunotherapy including dendritic cell (DC) vaccination. In a recently published ... Read more...
Intestinal mucosal barrier function in health and disease.
30 Oct 2009 Mucosal surfaces are lined by epithelial cells. These cells establish a barrier between sometimes hostile external environments and the internal milieu. However, mucosae are also responsible for nutrient absorption and waste secretion, which require ... Read more...
New insights into the differentiation and function of T follicular helper cells.
30 Oct 2009 The seminal studies characterizing T follicular helper (T(FH)) cells described a non-polarized CD4(+) T cell population with a unique ability to home to B cell follicles and to induce antibody production by B cells. In the past few years, the study ... Read more...
Latest indexed articles for 'Cytokines - Immunology'
These are the very latest articles for this heading:
- Immune responses in patients with metastatic renal cell carcinoma treated with dendritic cells pulsed with tumor lysate. 30 Oct 2009
- Intestinal mucosal barrier function in health and disease. 30 Oct 2009
- New insights into the differentiation and function of T follicular helper cells. 30 Oct 2009
- Cytokines decrease expression of interleukin-6 signal transducer and leptin receptor in central nervous system glia. 30 Oct 2009
- The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses. 14 Oct 2009
- Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases. 14 Oct 2009
- Gut immune balance is as easy as S-F-B. 14 Oct 2009
- Langerhans cells suppress contact hypersensitivity responses via cognate CD4 interaction and langerhans cell-derived IL-10. 13 Oct 2009
- Dominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion. 13 Oct 2009
- PU.1 regulates TCR expression by modulating GATA-3 activity. 13 Oct 2009
- Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase. 6 Oct 2009
- Transcriptional control of the inflammatory response. 29 Sep 2009
- Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91. 29 Sep 2009
- Glucocorticoid sensitivity of lipopolysaccharide-stimulated chronic obstructive pulmonary disease alveolar macrophages. 29 Sep 2009
- Cytokine and anti-cytokine therapy in asthma: ready for the clinic? 29 Sep 2009
- T cell receptor signaling induced by an analog peptide of type II collagen requires activation of Syk. 29 Sep 2009
- Chemo-metabolic regulation of immune responses by Tregs.
29 Sep 2009 - Cutting Edge: OX40 agonists can drive regulatory T cell expansion if the cytokine milieu is right. 26 Sep 2009
- Enhanced dendritic cell-induced immune responses mediated by the novel C-type lectin receptor mDCAR1. 26 Sep 2009
- Differential effect of IL-27 on developing versus committed Th17 cells. 26 Sep 2009
See a longer list of these articles.
Technical information about 'Cytokines'
Definition: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Registry Number: 0
Descriptor UI: D016207
Alternative terms: Cytokines;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; drug effects; ultrastructure;
Tree Number: D12.644.276.374; D12.776.467.374; D23.529.374;
History Note: 91