Cytoskeletal Proteins - Metabolism
Research News and Information

Sunday, November 22, 2009

Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.

2 Nov 2009 Leucine-rich repeat kinase 2 (LRRK2) functions as a putative protein kinase of ezrin, radixin, and moesin (ERM) family proteins. A Parkinson's disease-related G2019S substitution in the kinase domain of LRRK2 further enhances the phosphorylation of ... Read more...

Protein cytoskeleton and overexpression of Na(+),K(+)-ATPase in opossum kidney cells.

30 Oct 2009 Previous studies have shown that over time in culture opossum kidney (OK) cells are endowed with increased Na(+),K(+)-ATPase activity and expression (Silva et al., 2006, J Membr Biol 212:163-175; Silva and Soares-da-Silva, 2007, Am J Physiol Regul ... Read more...

A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.

5 Oct 2009 Multidomain scaffolding proteins organize the molecular machinery of neurotransmitter vesicle dynamics during synaptogenesis and synaptic activity. We find that domains of five active zone proteins converge on an interaction node that centers on the ... Read more...

Latest indexed articles for 'Cytoskeletal Proteins - Metabolism'

These are the very latest articles for this heading:

• Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. 2 Nov 2009
• Protein cytoskeleton and overexpression of Na(+),K(+)-ATPase in opossum kidney cells. 30 Oct 2009
• A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1. 5 Oct 2009
• Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid. 23 Sep 2009
• Novel compound with potential of an antibacterial drug targets FtsZ protein. 12 Sep 2009
• Promoting assembly and bundling of FtsZ as a strategy to inhibit bacterial cell division: a new approach for developing novel antibacterial drugs. 12 Sep 2009
• Establishment of cohesion at the pericentromere by the Ctf19 kinetochore subcomplex and the replication fork-associated factor, Csm3. 2 Sep 2009
• Targeting FtsZ for antibacterial therapy: a promising avenue. 30 Aug 2009
• Bacterial cell division: assembly, maintenance and disassembly of the Z ring. 30 Aug 2009
• The crystal structure of human pyrin b30.2 domain: implications for mutations associated with familial Mediterranean fever. 29 Aug 2009
• Mycoplasma pneumoniae cytoskeletal protein HMW2 and the architecture of the terminal organelle. 26 Aug 2009
• Involvement of HFq protein in the post-transcriptional regulation of E. coli bacterial cytoskeleton and cell division proteins. 20 Aug 2009
• Immunohistochemical localisation of PDE5 in rat lung during pre- and postnatal development. 18 Aug 2009
• Behaviorally evoked transient reorganization of hippocampal spines. 8 Aug 2009
• Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling. 3 Aug 2009
• Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting Rho kinase-mediated Ezrin phosphorylation at threonine 567. Aug 2009
• Induction of Wnt5a-expressing mesenchymal cells adjacent to the cloacal plate is an essential process for its proximodistal elongation and subsequent anorectal development. 30 Jul 2009
• Cytoplasmic Ig-domain proteins: cytoskeletal regulators with a role in human disease. 30 Jul 2009
• Proteomic analysis of chemonaive pediatric osteosarcomas and corresponding normal bone reveals multiple altered molecular targets. 30 Jul 2009
• Proteomic analysis of IgE-mediated secretion by LAD2 mast cells. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Cytoskeletal Proteins'

Definition: Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible.

Registry Number: 0

Descriptor UI: D003598

Alternative terms: Cytoskeletal Proteins; Proteins, Cytoskeletal;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.220;

History Note: 85

Technical Notes: /biosyn /drug eff /physiol permitted; do not use /analogs