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Cytoskeletal Proteins
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Definition of 'Cytoskeletal Proteins'

Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible.

Common names: Cytoskeletal Proteins; Proteins, Cytoskeletal

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Sunday, November 22, 2009

The Janus-faced role of ezrin in "linking" cells to either normal or metastatic phenotype.

13 Nov 2009 In the majority of eukaryotic cells, the ezrin, radixin and moesin (ERM) proteins are involved in many physiologic functions including regulation of actin cytoskeleton, control of cell shape, adhesion, motility and modulation of signal transduction ... Read more...


Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.

2 Nov 2009 Leucine-rich repeat kinase 2 (LRRK2) functions as a putative protein kinase of ezrin, radixin, and moesin (ERM) family proteins. A Parkinson's disease-related G2019S substitution in the kinase domain of LRRK2 further enhances the phosphorylation of ... Read more...


Protein cytoskeleton and overexpression of Na(+),K(+)-ATPase in opossum kidney cells.

30 Oct 2009 Previous studies have shown that over time in culture opossum kidney (OK) cells are endowed with increased Na(+),K(+)-ATPase activity and expression (Silva et al., 2006, J Membr Biol 212:163-175; Silva and Soares-da-Silva, 2007, Am J Physiol Regul ... Read more...

 

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Technical information about 'Cytoskeletal Proteins'

Definition: Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible.

Registry Number: 0

Descriptor UI: D003598

Alternative terms: Cytoskeletal Proteins; Proteins, Cytoskeletal;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.220;

History Note: 85

Technical Notes: /biosyn /drug eff /physiol permitted; do not use /analogs

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