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D-Amino-Acid Oxidase - Genetics
Research News and Information
Sunday, November 22, 2009
2 Aug 2009
D-amino acid oxidase (DAAO) has recently become of interest as a biocatalyst for industrial applications and for therapeutic treatments. It has been used in gene-directed enzyme prodrug therapies, in which its production of H2O2 in tumor cells can ... Read more...
DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study.
10 May 2009
BACKGROUND: Several studies of the dystrobrevin-binding protein 1 gene (DTNBP1), neuregulin 1 (NRG1), D-amino-acid oxidase (DAO), DAO activator (DAOA, G72), and metabotropic glutamate receptor 3 (GRM3) genes have suggested an association between ... Read more...
12 Feb 2009
Differences in the levels of the glutamate-related amino acids glycine and serine in brain/plasma between schizophrenic patients and normal subjects and changes in the plasma concentrations of these amino acids according to the clinical course have ... Read more...
Latest indexed articles for 'D-Amino-Acid Oxidase - Genetics'
These are the very latest articles for this heading:
- Optimization of D-amino acid oxidase for low substrate concentrations--towards a cancer enzyme therapy.
2 Aug 2009 - DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study.
10 May 2009 - Association analysis of glycine- and serine-related genes in a Japanese population of patients with schizophrenia.
12 Feb 2009 - Establishment of a cryopreservation method for the industrial use of D-amino acid oxidase-overexpressing Escherichia coli.
5 Feb 2009 - Molecular cloning and expression in Escherichia coli of an active fused Zea mays L. D-amino acid oxidase.
30 Jan 2009 - Simple and rapid genotyping of D-amino acid oxidase gene recognizing a crucial variant in the ddY strain using microchip electrophoresis.
30 Jan 2009 - Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in mice.
28 Dec 2008 - Investigation of G72 (DAOA) expression in the human brain.
9 Dec 2008 - Association of DAO and G72(DAOA)/G30 genes with bipolar affective disorder.
3 Sep 2008 - High soluble expression of D-amino acid oxidase in Escherichia coli regulated by a native promoter.
10 Aug 2008 - Transfection of the DAAO gene and subsequent induction of cytotoxic oxidative stress by D-alanine in 9L cells.
30 Jul 2008 - Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase.
3 Jul 2008 - D-amino acid oxidase activity and expression are increased in schizophrenia.
29 Jun 2008 - [Fusion expression of D-amino acid oxidase from Trignoposis variabilis with maltose binding protein and Vitreoscilla hemoglobin]
30 May 2008 - Biosilicification of dual-fusion enzyme immobilized on magnetic nanoparticle.
30 May 2008 - [Disease-oriented enzymology in D-amino acid metabolism]
30 Mar 2008 - Properties and applications of microbial D-amino acid oxidases: current state and perspectives.
13 Dec 2007 - Engineering the properties of D-amino acid oxidases by a rational and a directed evolution approach.
29 Nov 2007 - Evidence for association and epistasis at the DAOA/G30 and D-amino acid oxidase loci in an Irish schizophrenia sample.
3 Oct 2007 - No association between polymorphisms of DAO and DAOA genes and homicidal behaviors in Korean schizophrenia.
29 Sep 2007
See a longer list of these articles.
Technical information about 'D-Amino-Acid Oxidase'
Chemical name: D-Amino-acid:oxygen oxidoreductase (deaminating)
Registry Number: EC 1.4.3.3
Descriptor UI: D003605
Alternative terms: D-Amino-Acid Oxidase; D Amino Acid Oxidase; Oxidase, D-Amino-Acid; dextro-Amino Acid Oxidase; Acid Oxidase, dextro-Amino; Oxidase, dextro-Amino Acid; dextro Amino Acid Oxidase; D-Amino Acid Dehydrogenase; Acid Dehydrogenase, D-Amino; D Amino Acid Dehydrogenase; Dehydrogenase, D-Amino Acid;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;
Tree Number: D08.811.682.664.500.125;
Online Note: use D-AMINO-ACID OXIDASE to search D-AMINO ACID OXIDASE 1974-94 & D-AMINOACID OXIDASE 1966-73
History Note: 95; was D-AMINO ACID OXIDASE 1974-94, was D-AMINOACID OXIDASE 1963-73 (Prov 1963-65)