Dendritic Spines - Physiology
Research News and Information

Sunday, November 22, 2009

Angelman syndrome: current understanding and research prospects.

30 Oct 2009 Angelman syndrome is a neurogenetic disorder characterized by developmental delay, severe intellectual disability, absent speech, exuberant behavior with happy demeanor, motor impairment, and epilepsy, due to deficient UBE3A gene expression that may ... Read more...

Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity.

12 Oct 2009 Estrogen, in addition to its genomic effects in brain, causes rapid and reversible changes to synaptic operations. We report here that these acute actions are due to selective activation of an actin-signaling cascade normally used in the production ... Read more...

Corticosterone reduces dendritic complexity in developing hippocampal CA1 neurons.

30 Aug 2009 Although prolonged stress and corticosteroid exposure induce morphological changes in the hippocampal CA3 area, the adult CA1 area is quite resistant to such changes. Here we addressed the question whether elevated corticosteroid hormone levels ... Read more...

Latest indexed articles for 'Dendritic Spines - Physiology'

These are the very latest articles for this heading:

• Angelman syndrome: current understanding and research prospects. 30 Oct 2009
• EphB maintains dendritic spine morphology through focal adhesion kinase. 19 Oct 2009
• Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity. 12 Oct 2009
• Corticosterone reduces dendritic complexity in developing hippocampal CA1 neurons. 30 Aug 2009
• Age-dependent impairment of spine morphology and synaptic plasticity in hippocampal CA1 neurons of a presenilin 1 transgenic mouse model of Alzheimer's disease. 10 Aug 2009
• Neuronal circuit remodeling in the contralateral cortical hemisphere during functional recovery from cerebral infarction. 10 Aug 2009
• Behaviorally evoked transient reorganization of hippocampal spines. 8 Aug 2009
• Cholinergic modulation of multivesicular release regulates striatal synaptic potency and integration. 7 Aug 2009
• Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis. 3 Aug 2009
• Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines. 3 Aug 2009
• Synaptic potentiation induces increased glial coverage of excitatory synapses in CA1 hippocampus. 30 Jul 2009
• Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes. 20 Jul 2009
• Morphological and electrophysiological features of motor neurons and putative interneurons in the dorsal vagal complex of rats and mice. 16 Jul 2009
• GABA(A) receptor membrane trafficking regulates spine maturity. 12 Jul 2009
• Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport. 8 Jul 2009
• Long-term potentiation in isolated dendritic spines. 21 Jun 2009
• Dendritic spine formation and stabilization. 8 Jun 2009
• Kinase-dead knock-in mouse reveals an essential role of kinase activity of Ca2+/calmodulin-dependent protein kinase IIalpha in dendritic spine enlargement, long-term potentiation, and learning. 8 Jun 2009
• Synapse development and plasticity: roles of ephrin/Eph receptor signaling. Jun 2009
• Membrane potential changes in dendritic spines during action potentials and synaptic input. 25 May 2009

See a longer list of these articles.

Technical information about 'Dendritic Spines'

Definition: Spiny processes on DENDRITES, each of which receives excitatory input from one nerve ending (NERVE ENDINGS). They are commonly found on PURKINJE CELLS and PYRAMIDAL CELLS.

Descriptor UI: D049229

Alternative terms: Dendritic Spines; Dendritic Spine; Spine, Dendritic; Spines, Dendritic;

Allowable Qualifiers: classification; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; ultrastructure; ultrasonography; chemistry; virology; genetics;

Tree Number: A08.663.256.200; A11.284.180.225.169; A11.671.240.169;

History Note: 2005